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临床试验/NCT02999503
NCT02999503Unknown不适用

Nutritional and Environmental Conditions in Attention Deficit Hyperactivity Disorder

Hospital El Escorial2 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2016年11月最近更新:
适应症

试验速览

阶段
不适用
入组人数
70
试验地点
2
主要终点
Change in Conners

研究概览

简要总结

In this study the investigators aim to investigate the relationship between environmental factors, lifestyle and symptoms of Attention Deficit Hyperactivity Disorder (ADHD). Initially the investigators intend to measure the relationship between nutritional quality, exercise and sleep and ADHD symptoms. And then measure whether a change made in the diet can improve the symptoms of ADHD.

详细描述

The Attention Deficit Hyperactivity Disorder is a neurobiological chronic disorder, symptomatically evolutionary and of probable genetic transmission that affects between 5 and 10% of the child population.

The current opinion on the etiology of the disorder focuses on a failure in the development of brain circuits in which inhibition and self-control, critical functions to perform any task, gets supported. In addition, there is greater evidence of knowledge of the genetic influence as a major part of the etiology of ADHD. Studies suggest that ADHD is familiar and that genetic influences may contribute to its etiology from moderate to high phenotypic expression. Current studies have identified significant associations with several candidate genes for this disorder, including DAT1, DRD4, DRD5, 5HTT, HTR1B or SNAP25.

Meta-analytical studies are needed to develop a more personalized treatment for ADHD. Other factors associated with ADHD are inadequate lifestyles by parents, especially during the gestation period in the case of the mother. ADHD treatment includes the use of medication and psychosocial and educational support

FOOD, NUTRITION AND ADHD: A NEW PARADIGM OF THERAPY?

Despite the above, with the use of internet many hypotheses have emerged, not yet proven, many in relation to food of patients with ADHD, in which a single focus is exposed as the determinant factor: heavy metals; gluten and dairy; additives; or intake of certain supplements.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
8 Years 至 16 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Both genders
  • Ages 8-16 years
  • ADHD proved

排除标准

  • Presence of serious or chronic illnesses: leukemia, spinal cord injury, celiac disease, pancreatitis, hepatitis, HIV...

结局指标

主要结局

Change in Conners

时间窗: At 3 and 6 months

Conners conduct questionnaire: attention deficit and disruptive behavior disorders; hyperactivity; and combined type.

次要结局

  • Change in exercise markers(At 3 and 6 months)
  • Change in Anthropometry I(At 3 and 6 months)
  • Change in sleep(At 3 and 6 months)
  • Change in Anthropometry II(At 3 and 6 months)
  • Change in Anthropometry III(At 3 and 6 months)
  • Change in Anthropometry IV(At 3 and 6 months)
  • Change in nutritional habits(At 3 and 6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Blumenfeld Olivares JA

Pediatrician, Responsible of Pediatric Endocrinology. Principal Investigator.

Hospital El Escorial

研究点 (2)

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