SMR/Theta Neurofeedback Training Improves Cognitive Performance and EEG Activity in Elderly With Mild Cognitive Impairment: A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 主要终点
- Rey Auditory Verbal Learning test
研究概览
简要总结
This is a non-pharmacological pilot study showing the improvement of a SMR/theta neurofeedback training program on cognitive performance and EEG activity in Elderly with Mild Cognitive Impairment.
详细描述
Neurofeedback training (NF) as self-regulation method of brain activity, may be beneficial in elderly with mild cognitive impairment. In this pilot study, the investigators studied whether a sensorimotor(SMR)/theta NF training could improve cognitive performance and brain electrical activity in a sample group of elderly patients with mild cognitive impairment. Twenty participants performed an electroencephalography recording, a battery of neuropsychological tests before the neurofeedback training program (T0), following the neurofeedback training program (T1) and 1-month follow-up (T2).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 90 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of Mild Cognitive Impairment
- •education level of 9 years of studies minimum
- •righthandedness
- •subjective memory complaint confirmed by an informant
- •a Mini Mental Status Examination score >
- •preserve activity of daily living and absence of dementia.
排除标准
- •elderly persons who were under guardianship
- •resident in nursing facilities
- •neurological disease, psychiatric disease
- •and involved in another cogniitve intervention.
结局指标
主要结局
Rey Auditory Verbal Learning test
时间窗: Assessment at baseline, change from baseline to 11 weeks immediately after the NF training and 1 month follow-up
Assessment of verbal learning in episodic memory, evaluating the ability to encode, combine, store and long-term consolidation process.
次要结局
- Relative power for delta, theta, alpha, sensorimotor and lower beta frequency bands.(Assessment at baseline, change from baseline to 11 weeks immediately after the NF training and 1 month follow-up)
研究者
Fabienne Marlats
Neuropsychologist
Broca Hospital