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临床试验/NL-OMON31496
NL-OMON31496尚未招募2 期

The effect of inhaled heparin on pulmonary coagulation activation and vascular permeability in mechanically ventilated patients with acute lung injury / acute respiratory disress syndrome - HEPALI study

Academisch Medisch Centrum0 个研究点目标入组 26 人开始时间: 待定最近更新:
适应症

试验速览

阶段
2 期
状态
尚未招募
入组人数
26

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • All patients who are intubated and mechanically ventilated in the ICU, who meet the International Consensus Criteria of ALI/ARDS
  • Inclusion Criteria:
  • -Informed consent
  • -Age 18-80 years
  • -Recent onset of ALI/ARDS (i.e. <48 hrs)

排除标准

  • Exclusion criteria
  • -Acute bleeding at any site
  • -Increased risk of bleeding:
  • Platelets< 50 * 109 / L
  • PT > 20 sec
  • APTT > 60 sec
  • Within 24 hours after major surgery
  • -Proven of clinically suspected heparin induced thrombocytopenia
  • -Hemorrhagic diathesis
  • -Heparin allergy
  • -Pregnancy or breast feeding

研究者

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