NL-OMON31496尚未招募2 期
The effect of inhaled heparin on pulmonary coagulation activation and vascular permeability in mechanically ventilated patients with acute lung injury / acute respiratory disress syndrome - HEPALI study
适应症
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 26
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99(—)
入选标准
- •All patients who are intubated and mechanically ventilated in the ICU, who meet the International Consensus Criteria of ALI/ARDS
- •Inclusion Criteria:
- •-Informed consent
- •-Age 18-80 years
- •-Recent onset of ALI/ARDS (i.e. <48 hrs)
排除标准
- •Exclusion criteria
- •-Acute bleeding at any site
- •-Increased risk of bleeding:
- •Platelets< 50 * 109 / L
- •PT > 20 sec
- •APTT > 60 sec
- •Within 24 hours after major surgery
- •-Proven of clinically suspected heparin induced thrombocytopenia
- •-Hemorrhagic diathesis
- •-Heparin allergy
- •-Pregnancy or breast feeding
研究者
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