Randomized controlled clinical investigation to evaluate treatment concept forreconstruction of atrophied alveolar ridge using Collagenated Xenogeneic Bone Block(CXBB) compared to autogenous bone block (ABB) treatment

Geistlich Pharma AG0 个研究点目标入组 67 人开始时间: 2017年4月12日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•- General contraindications for dental and/or surgical treatments
•- Periodontitis
•- Peri-implantitis
•- Probing depth > 4mm at the adjacent teeth
•Inadequate oral hygiene (PI>1)
•- Knife-edge morphology of the alveolar ridge
•- Insufficient bone for bone block harvesting from ramus mandibulae
•- Edentulous area not larger than 4 missing teeth
•- Implants adjacent to the surgical site
•- Inflammatory disease of oral cavity
•- Immunological impairment
•- Allergy to collagen
•- Diabetes
•- History of myeloma, respiratory tract cancer, breast cancer, prostate cancer or kidney cancer requiring chemotherapy or radiotherapy within the past five years
•- Previous, concurrent or planned radiotherapy of head area
•- Concurrent or previous immunosuppressant, bisphosphonate, high-dose or long-term corticosteroid therapy
•- Smokers or subjects who did not quit smoking at least 3 months prior to the surgery
•- Pregnant or lactating women
•- Women of child bearing age, who are not using a highly effective method of birth control
•- Participation in an investigational device, drug or biologics study within the last 26 weeks
•prior to the study start
•- Participation in any other clinical investigation during the study

发起方