CTRI/2023/03/050974已完成1 期
A Randomized, Double Blind, Placebo Controlled Pilot Study to Evaluate the Effect of Ashwagandha (Withania somnifera) Extract in improving memory in adults with mild cognitive impairment
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Age between 25 to 65 years
- •2. Participants with mild, subjective symptoms of memory impairment
- •3. Participants with no impairment in Social and Occupational Functioning
- •4. Instrumental Activities of Daily Life (IADL) score > 6
- •5. Montreal Cognitive Assessment (MoCA) Score 18-25
- •6. Clinical Dementia Rating (CDR) Global score < 0.5
- •7. Mini-Mental State Examination (MMSE) score 20-23
- •8. Vitamin B12 (Serum) 200-900pg/mL
排除标准
- •1. Known neuropsychiatric conditions including depression
- •2. Persistent endocrine disorders
- •3. Uncontrolled hypertension
- •4. Diabetes mellitus
- •5. Drug dependence or addiction
- •6. Use of alcohol
- •7. Psychotropic drugs or drugs or alternative medicines for memory enhancement, or any severe comorbid medical condition.
- •8. Pregnant or lactating women and
- •9. Subjects with known hypersensitivity to ashwagandha
- •10. Other than ashwagandha in the treatment group, the use of nootropic agents or anticholinesterase drugs will be prohibited during the study.
- •11. History of significant brain disorders (e.g., stroke or epilepsy);
- •12. Use of any type of dementia-delaying medication;
- •13. Head trauma with post-traumatic loss of consciousness for at least 30 min during the lifespan
- •14. Brain damaged patients (brain tumour; penetrating head injury; closed head injury; cerebral vascular accident; cerebral abscess; cerebral atrophy; subdural hematoma; temporal lobectomy for epilepsy; dementia paralytica; congenital anomaly of brain)
研究者
相似试验
招募中
1 期
A clinical trial conducted to determine the safety and tolerability of ORE1001 in patient suffering with Ulcerative Colitis.CTRI/2010/091/000097ORE Pharmaceuticals Ltd.50
进行中（未招募）
不适用
A Randomized, double-blind, placebo-controlled pilot study of KB001 in mechanically-ventilated patients colonized with pseudomonas aeruginosaEUCTR2007-006764-29-FRKaloBios Pharmaceuticals, Inc.
进行中（未招募）
1 期
Passion flower and stressSince only healthy volunteers will be included in this study, there is no medical condition to be examined. The indication for PASCOFLAIR® is nervous restlessness, a subclinical state of stress-sensitivity.EUCTR2011-006129-17-DEPASCOE Pharmazeutische Präparate GmbH60
招募中
2 期
Effect of centhaquine on cardiovascular parameters in patients with hypovolemic shock.CTRI/2023/12/060444Aman Hospital and Research Centre
进行中（未招募）
1 期
A Randomized pilot study to evaluate the safety and efficacy of Cinryze (C1-Esterase Inhibitor (human)) for the treatment of graft rejection in kidney transplant patientsEUCTR2012-000441-12-DEVIROPHARMA Incorporated20