NCT00700596已完成早期 1 期
Psychotomimetic Effects of Kappa Opioid Receptor Agonist Salvinorin A in Healthy Controls
适应症
干预措施
相关药物
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 105
- 试验地点
- 1
- 主要终点
- Positive and Negative Syndrome Scale, Clinician Administered Dissociative Symptoms Scale, Visual Analog Scale, Assessment of Opioid Effects, Cognitive Testing
研究概览
简要总结
This study evaluates the effects of Salvinorin A (SA). SA is the active ingredient of the plant Salvia divinorum that is known to have been used by Mexican Indians as part of religious rituals. The purpose of this project is to understand what people experience when they consume Salvinorin A.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Previous exposure to inhaled Salvinorin A (SA).
排除标准
- 未提供
研究组 & 干预措施
1
Active Comparator
Salvinorin A (SA)
干预措施: Salvinorin A (Drug)
2
Placebo Comparator
Control or Placebo SA
干预措施: Placebo (Drug)
结局指标
主要结局
Positive and Negative Syndrome Scale, Clinician Administered Dissociative Symptoms Scale, Visual Analog Scale, Assessment of Opioid Effects, Cognitive Testing
时间窗: Time Frame: -30, +10, +30, +90, +120. +200
次要结局
未报告次要终点
研究者
Mohini Ranganathan
Associate Professor of Psychiarty
Yale University
研究点 (1)
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