跳至主要内容
临床试验/CTRI/2025/01/078927
CTRI/2025/01/078927招募中2 期

An Evaluation of efficacy of Mulethi Churna in Raktakshaya and Jatharagni w.s.r. to "Raktakshaye mandah sanjayte analah".

Department of Kriya Sharir Shri NPA Govt Ayurved college Raipur Chhattisgarh 4920101 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年2月3日最近更新:

试验速览

阶段
2 期
状态
招募中
发起方
入组人数
30
试验地点
1
主要终点
Oral administration of mulethi churna will lead to an improvement in Raktakshaya.

研究概览

简要总结

Maintenance of health of healthy person is the primary aim of the Ayurvedic classics as mentioned in

Charaka Samhita. Arogya is dependend on Doshasamyata, Dhatu Samyata, Agni Samyata and Samyag

Malakriya. Aarogya is characterised by free from any Elements excellence of voice and complersion,

proper metabolism, high physical, and mental strength, desired for food with appeteting in proper time

and proper digestion, appropriate sleep without any dream, proper empulsion of flatus, urine, stool and

semen excellence in motor and sensory perception.

On giving importance to Jatharagni Acharya Charak has mentioned its povital role in maintaining

health and longevity. Sustaining of life is depends on Jatharagni as the cessation of Agni leads to the

death of an individual.

Acharya Sushruta’s perspective underscores the close relationship between Pitta and Agni in Ayurveda.

He suggests that Pitta, one of the three doshas, is intimately linked to the concept of Agni within the

body.

Ayurveda categorizes Agni into three major types based on their locations and substrates they act upon:

Raktagni, a subtype of Dhatvagni (tissue metabolism), is responsible for the digestion and metabolism

of Rakta dhatu. Ranjak Pitta works in conjunction with Raktagni, simultaneously aiding in the

formation and maintenance of Rakta Dhatu.This collaboration between Raktagni and Ranjak Pitta

highlights the intricate interplay between digestive fire (jatharagni) and the formation of blood tissue

(Rakta Dhatu) in Ayurveda.So in depletion of Rakta Dhatu, known as Raktakshaya, lead to Mandagni,

or low digestive fire.

Raktakshaya symptoms according to Acharya Charak are Parusha, Sfutita, Mlana, Twagruksha, Rakta

Sankshaye and according to Acharya Sushruta are Shonita Kshaye, Twak Parushya, Amla

Shitaprarthna, Sirasaithilya.

Raktkshaya co-related with the anaemia, particularly nutritional deficiency anaemia, where the

haemoglobin level in the blood is diminished from normal.

Mulethi possesses the qualities like Madhura in rasa and Vipak, guru, Snigdha in Guna, Seeta in

Virya8& Sonitasthapak.

According to old researches, a lot of work has been done related to Rakta Dhatu and it’s Kshaya

(Raktalpata). The critical need for research to show how Rakta Dhatu Kshaya affects the digestive

power or jatharagni. It is important to study as various diseases are originated from Mandagni. In India

Raktadhatu Kshaya or anaemic patient seen more and more. According to the national family health

survey (NFHS – 5) about 40 % of women & 18.9% of men are moderately anaemic, 1% of both are

severely anaemic. Prevalence of anaemia in India rural areas (women 58.5%, men 27.4%) is highly than

urban areas (women 53.8%, men 20.4%)10, Prevalence of Anaemia in Chhattisgarh rural areas (women

62.2%, men 28.9%) and urban areas (women 56.5%, men 22.5%)10. Most of the anaemia are due to

inadequate supply of nutrients like iron, folic acid and vitamin B12, A, C, etc. Most cases of anaemia

are linked to deficiencies in essential nutrients like iron, folic acid, amino acids, and various vitamins.

It suggests that Rakta Dhatu Kshaya can be prevented through proper nutrition and adherence to the

principles of Pathya Ahara-Vihara, as prescribed in Ayurveda.

Mulethi is Madhu in Rasa, Guru, Snigdha in Guna, Madhur in Vipaka, Sheet Virya and Shonita Sthapak

it can be increases blood and Jatharagni simultaneously. So I choose this topic to establish the relation

of Rakta dhatu and Jatharagni.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
15.00 Year(s) 至 49.00 Year(s)(—)
性别
All

入选标准

  • (1) Patients with age group 15 to 49 years.
  • (2) Patients irrespective of gender, marital status , socio-economics status, religion, occupation etc.
  • (3) Patients having haemoglobin range 7-10 gm% in female and 9-13% in male.
  • (4) Patients of nutritional deficiency Anaemia only.
  • (5) Patients who agree to sign consent form .

排除标准

  • Patient with age below 15 years and above 49 years.
  • Patient having Haemoglobin range less than 7gm% and more than 10 gm% in female less than 9gm% and more than 13 gm% in male
  • Pregnant and lactating women.
  • Any haemorrhagic condition.
  • Patients suffering from any systemic disease like renal, thyroid disorders etc.
  • Patient suffering from haematological disorders such sickle cell anaemia and thalassemia.
  • Patient suffering from Aplastic anaemia & haemolytic anaemia.
  • Patient not giving consent.

结局指标

主要结局

Oral administration of mulethi churna will lead to an improvement in Raktakshaya.

时间窗: 2 months

次要结局

  • Consumption of Mulethi Churna will lead to an improvement in Jatharagni(2 months)

研究者

发起方
Department of Kriya Sharir Shri NPA Govt Ayurved college Raipur Chhattisgarh 492010
申办方类型
Other [Government Ayurved College ]
责任方
Principal Investigator
主要研究者

DR FIROJ KUMAR

Shri NPA Govt Ayurved college Raipur Chhattisgarh 492010

研究点 (1)

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