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临床试验/NCT07635043
NCT07635043尚未招募4 期

Efficacy of Topical Tapinarof Versus Betamethasone in the Treatment of Plaque Psoriasis

Pakistan Institute of Medical Sciences1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2026年8月1日最近更新:

试验速览

阶段
4 期
状态
尚未招募
入组人数
120
试验地点
1

研究概览

简要总结

To assess the effectiveness of topical tapinarof to topical betamethasone in patients with mild to moderate plaque psoriasis presenting to tertiary care hospital in Islamabad

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 18 years-65 years
  • Clinically diagnosed plaque psoriasis involving body surface area ( BSA) of 2-20% (mild to moderate severity)
  • Disease duration of at least 6 months
  • Willing and able to provide written informed consent
  • Not currently using any other topical and systematic psoriasis therapy, or willing to undergo a washout period (2 weeks for topical therapies)

排除标准

  • Severe psoriasis (BSA >20% or requiring systemic therapy)
  • Pregnant and lactating mothers
  • Known hypersensitivity to Tapinarof or any of its excipients
  • Concurrent dermatological conditions that may interfere with assessment e.g fungal infections,atopic dermatitis
  • Use of systemic immunosuppressants (methotrexate, cyclosporine, biologics ) or phototherapy within 4 weeks before enrollment
  • History of malignancy or current active infection
  • Known hypersensitivity to betamethasone or Tapinarof
  • Use of powerful topical corticosteroids within two weeks previously

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Noor Ul Ain

Dermatology resident

Pakistan Institute of Medical Sciences

研究点 (1)

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