NCT05335746Unknown不适用
Chorioretinal Changes in Vitiligo Patients on Therapy
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Percentage of vessel density (VD) in superficial and deep retinal layer.
研究概览
简要总结
Vitiligo patients on systemic and local therapy may have some ocular adverse effects associated with the disease and its therapy.
详细描述
Chorioretinal changes associated with vitiligo therapy could address patients visual acuity and life style. Early detection of these changes can help these patients to evade such adverse effects.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •vitiligo patients on systemic and local therapy that regularly visit dermatology clinic at banha university.
- •normal subjects seeking regular ophthalmic examination at ophthalmology clinic at banha university.
排除标准
- •patients with known chronic retinal diseases that may alter OCT-A parameters as age related macular degeneration and diabetic retinopathies.
- •patients that refuse to participate in this study.
结局指标
主要结局
Percentage of vessel density (VD) in superficial and deep retinal layer.
时间窗: Immediately after OCT-A for each eye and at one month of follow-up.
Percentage (%) of superficial and deep vessel density changes in both groups measured by OCT-A software to asses retinal ischemia.
次要结局
- Foveal avascular zone (FAZ) in millimeter (mm).(Immediately after OCT-A for each eye and at one month of follow-up.)
研究者
Ahmed Abdelshafy
Clinical professor
Benha University
研究点 (1)
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