Fermented Grape Drinks Made of Fermented Grapes With Fruit and Vegetable Powder to Explore Whether it Can Improve the Skin's Condition and Achieve Anti-inflammatory Effects.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- skin moisture
研究概览
简要总结
60 subjects were recruited and divided into placebo group and fermented grape drinks group.
详细描述
In this study, using a fermented grape drinks made of fermented grapes with fruit and vegetable powder to explore whether it can improve the skin's condition and achieve anti-inflammatory effects. Sixty subjects were recruited and divided into placebo group and fermented grape drinks group. After drinking for 8 weeks, skin test and blood biochemical analysis were performed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Large pores
- •Dark yellow complexion
- •Sagging skin
排除标准
- •Skin disorders
- •Liver diseases
- •Kidney diseases
- •Allergy to cosmetics, drugs, or foods
- •Pregnant and lactating women
- •People who had any cosmetic procedures before 4 weeks of the study
- •Area of facial spot over 3 cm2
- •People who took collagen supplements in the past 3 months.
研究组 & 干预措施
placebo group
subjects drank 50 ml , 1 bottle a day for 8 week
干预措施: placebo group (Dietary Supplement)
fermented grape drinks
subjects drank 50 ml , 1 bottle a day for 8 week
干预措施: fermented grape drinks (Dietary Supplement)
结局指标
主要结局
skin moisture
时间窗: 8 week
The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then using probe system GL2000 \& MPA10 to examine skin moisture (The higher the value, the higher the gloss, no unit)
skin spot
时间窗: 8 week
The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then usig VISIA-CR to examine skin spot (The higher the value, the larger the pore area, mm2)
skin brightness
时间窗: 8 week
The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then using corneometer CM825 to examine skin brightness (The higher the value, the more water content, C.U., corneometer units )
inflammatory cytokines
时间窗: 8 week
The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then using ELISA kit to examine inflammatory cytokines (pg/ml)
skin elasticity
时间窗: 8 week
The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then using cutometer dual MPA580 to examine skin elasticity (The closer the R2 value is to 1, the better the elasticity and no unit)
skin wrinkle
时间窗: 8 week
The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then using VISIOSCAN-VC20 to examine skin wrinkle (The higher the value, the more wrinkles, surface evaluation of wrinkles, SEW)
次要结局
未报告次要终点