ISRCTN61534963已完成不适用

The activity of sulphadoxine-pyrimethamine plus artesunate (SP+AS) and SP+AS followed by a single dose of primaquine (0.75 mg/kg ) against gametocytes in Tanzanian children with uncomplicated falciparum malaria

The Netherlands Foundation for the Advancement of Tropical Research (NWO-WOTRO) (Netherlands)0 个研究点目标入组 100 人开始时间: 2006年12月4日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Age more than three years
•2. Residents of research area (5 km around the clinic)
•3. Willingness to come for complete scheduled follow-up
•4. Uncomplicated malaria with Plasmodium falciparum mono-infection
•5. Parasitaemia of 500,000 to 900,000 parasites/ul
•6. Temperature more than 37.5 and less than 39.5°C, or history of fever in the previous 24 hours
•7. No history of adverse reactions to SP or PQ treatment
•8. Understanding of the procedures of the study by parent or guardian and willing to participate by signing informed consent forms

•1. General signs of severe malaria or haemoglobin count less than 8 g/dl
•2. Presence of disease other than malaria causing febrile conditions
•3. Unwilling to participate and sign informed consent forms
•4. Eligibility for (or participation in) other malaria projects in the Korogwe area, notably the Intermittent Preventive Treatment of malaria in infants (IPTi) study

发起方

The Netherlands Foundation for the Advancement of Tropical Research (NWO-WOTRO) (Netherlands)