Non-invasive Intracranial Pressure Monitoring in Brain Tumor Patients: A Prospective Observational Study of Optic Nerve Sheath Diameter Dynamics
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- optic nerve sheath diameter dynamics
研究概览
简要总结
This research protocol focuses on the pre- and post-operative evaluation of ICP using non-invasive methods, particularly in the context of surgery for brain tumor removal. By utilizing ocular ultrasound to measure ONSD and ONSD/ETD ratios, this study hypothesizes that the utility of these parameters in monitoring ICP pre- and post-operative periods could be effective.
详细描述
This research protocol focuses on the pre- and post-operative evaluation of ICP using non-invasive methods, particularly in the context of brain tumor resection surgery. By utilizing ocular ultrasound to measure ONSD and ONSD/ETD ratios, this study hypothesizes that the utility of these parameters in monitoring ICP pre- and post-operative periods could be effective.
This study aims to evaluate the effectiveness of the ONSD and the ONSD/ETD ratio using ultrasound as a non-invasive method for measuring intracranial pressure pre- and post-operatively in brain tumor patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• Adult patients (>21 years) undergoing brain tumor resection surgery.
- •Preoperative imaging-confirmed diagnosis of the tumor.
- •American Society of Anesthesiologists (ASA) physical status II to IV
- •Consent to participate in the study.
排除标准
- •• Preexisting ocular conditions affecting the optic nerve or globe integrity, such as glaucoma, thyroid-associated ophthalmopathy, or other optic nerve diseases.
- •Combined ocular and optic nerve injuries at admission.
- •History of cranial trauma, prior neurosurgery, or lumbar puncture performed within 2 weeks before the measurement of optic nerve sheath diameter (ONSD).
- •History of subarachnoid hemorrhage (SAH).
- •Serious complications that could affect life expectancy, such as hematological disorders or malignancies.
- •Refusal to participate or withdrawal of consent at any stage.
结局指标
主要结局
optic nerve sheath diameter dynamics
时间窗: before (in the preoperative holding area) and after the surgery (immediate, 1,2, 4, 6, and 12 hr in ICU).
the measuremnt of optic nerve sheath diameter and optic nerve sheath diameter to transverse eyeball diamter ratio
次要结局
未报告次要终点
研究者
tarek abdel hay mostafa
principle investigator
Tanta University