JPRN-jRCTs031180231已完成未知
Multi-center randomized controlled trial to evaluate oral vitamin B12 treatment for vitamin B12 deficiency after total gastrectomy in gastric cancer patients
Rino Yasushi0 个研究点目标入组 78 人开始时间: 2019年3月11日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 78
研究概览
简要总结
The major findings of this study were that oral Vitamin B12 50010^-6g/day replacement is as effective and safe as oral Vitamin B12 150010^-6g/day replacement for Vitamin B12 deficiency.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 ot applicable（—）
- 性别
- All
入选标准
- •1:Histologically proven adenocarcinoma of the stomach and dignosed pathological stage I to III
- •2:Received R0 resection
- •3:Age ranging between 20 and 80 years
- •4:ECOG performance status 0-2
- •5:seremu vitamin B12 was under 200pg/ml
- •6:Peripheral neuropathy with vitamin B12
- •7:Sufficient oral intake
- •8:Sufficient organ function
- •9:Answer toPNQ test
- •10:Patients were given a written explanation of the study protocol and provided their written informed consent before participating.
排除标准
- •1:Synchronous or metachronous cancer (synchronous multiple cancers in the stomach included).
- •2:Allergic reaction to vitamin B12
- •3:Systemic treatment with vitamin B12
- •4:Peripheral neuropathy with other causes
- •5:Received adjuvant chemotherapy for gastric cancer
- •6:Any other medical conditions that made a patient unsuitable for inclusion in the study according to the opinion of the investigator were also considered to be exclusion criteria for this study
- •7:Other patients judged inappropriate by the examining physician
研究者
相似试验
已完成
不适用
Efficacy and Safety Study of Oral Eligen® B12 in Subjects With Low Serum CobalaminVitamin B 12 DeficiencyNCT01312831Emisphere Technologies, Inc.49
已完成
2 期
Evaluate the Neuroprotective Effect of Vitamin B6 and Vitamin B12 Against Vincristine Induced Neurotoxicity in Acute Lymphoblastic Leukaemia PatientsVincristine Induced NeurotoxicityAcute Lymphoblastic LeukaemiaNCT03593304Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh40
已完成
不适用
Vitamin B12 Biomarker Responses to SupplementationHealthyNCT04731948University of Ulster200
撤回
3 期
Placebo-Controlled Study of the Efficacy and Safety of BG00012 in Pediatric Subjects With Relapsing-Remitting Multiple Sclerosis (RRMS)Relapsing-Remitting Multiple SclerosisRelapsing Forms of Multiple SclerosisNCT02428218Biogen
已完成
2 期
High Dose Trial in COPDPulmonary Disease, Chronic ObstructiveNCT00128440Boehringer Ingelheim78