Perceived Social Status as a Determinant of Fat Accretion in Response to Excess Calories: the SSIB Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 主要终点
- Average 24 hour energy balance (24hr EB)
研究概览
简要总结
Investigators examined the associations between SSS, energy balance, food intake and changes in body composition following a high calorie lunch for 2 weeks.
详细描述
Subjective social status (SSS) is inversely associated with body fatness. The physiological and psychological effects of low social status may spur increased energy intake as a strategy to buffer against future food scarcity. Investigators' central hypothesis is that females with low SSS will not compensate for excess calorie consumption in a single large meal as well as individuals with high SSS, and will therefore remain in positive energy balance leading to body fat gain in response to daily large meals. Investigators' objective is to understand the influence of SSS on eating behavior, weight gain, and energetic compensation. Investigators conducted a 14-day feeding protocol that consisted of consumption of a lunch-time meal that was 60% of participants' estimated 24-hour energy requirements each day in female participants between 20-50 years, with a body mass index between 25- 30 kg/m2. Free-living food intake was recorded using the Remote Food Photography Method outside of the lab on days 1-2 (early), 7-8 (middle), and 12-13 (late), to measure compensation in response to the large lunch. 24-Hour energy balance, 24 hour intake and post-lunch energy intake were calculated for those days. Investigators measured body composition using Dual energy x ray absorptiometry (DXA), weight and resting energy expenditure at the baseline and at the end of the 14 days of the intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- Single (Participant)
盲法说明
Participants were blinded to the actual study aim. They were told that the aim of the study is to study the relationship between consumption of dietary macronutrient ratios and metabolic rate.
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •between 20-50 years
- •body mass index between 25- 30 kg/m2
排除标准
- •food allergies or food restrictions
- •engaged in any weight reduction program within the past 3 months
- •experienced any weight loss or gain of >5% of body weight in the past 6 months for any reason except post-partum weight loss
- •taking any medication that suppresses or stimulates appetite
- •undergone prior surgical procedures for weight control or liposuction
- •current smoker or has not smoked in less than 6 months
- •any major diseases including active cancer or cancer requiring treatment in the past 2 years (except non-melanoma skin cancer)
- •active or chronic infections (e.g., HIV or TB)
- •cardiovascular disease or event including hospitalization or therapeutic procedures for treatment of heart disease in the past 6 months
- •gastrointestinal disease
- •kidney disease
- •chronic obstructive airway disease requiring use of oxygen (e.g., emphysema or chronic bronchitis)
- •diabetes (type 1 or 2) and taking any anti-diabetic medications and/or controlling the disease via dietary manipulations
- •uncontrolled psychiatric disease
- •a recent or ongoing problem with drug abuse or addiction
- •consume more than three alcoholic drinks per day and has had 7 or more alcoholic beverages in a 24 hour period in the last 12 months
- •pregnant or less than 3 months post-partum
- •currently nursing or within 6 weeks of having completed nursing
- •anticipating a possible pregnancy during the study
研究组 & 干预措施
Dietary intervention
All participants consumed a meal that contains 60% of their energy daily energy requirement as a lunch time meal for 14 consecutive days.
干预措施: Dietary intervention (Behavioral)
结局指标
主要结局
Average 24 hour energy balance (24hr EB)
时间窗: Six time points ( Days 1, 2, 7, 8, 12 and 13) measured over the two week feeding protocol.
We measured 24-hr energy balance to assess the association of SSS with positive energy balance in response to a daily large meal perturbation. Twenty four hour energy balance was calculated for each time point as follows, and all six time points were averaged to get an average energy balance over the 2-week period: 24 hr Energy balance = Average 24 hr Energy intake / Resting Energy Expenditure \*1.4 For the early and middle time point 24EB calculations, baseline resting energy expenditure (REE) was used and for late 24hr EB, final REE obtained at the end of the study was used.
次要结局
- Percent changes in body weight(% change from baseline (day 0) to the end of the intervention period (day 14))
- Average 24 hour energy intake (24hr EI) over a two week period(Average of six time points ( Days 1, 2, 7, 8, 12 and 13) over a two week period)
- Changes in adjusted resting energy expenditure(change from baseline (day 0) to the end of the intervention period (day 14))
- Percent changes in body fat(% change from baseline (day 0) to the end of the intervention period (day 14))
- Post-lunch energy intake(Average of six time points (Days 1, 2, 7, 8, 12 and 13) over a two week period)
研究者
Emily Dhurandhar
Assistant Professor
Texas Tech University