EUCTR2015-005045-31-NL进行中（未招募）1 期
Switching to Tenofovir Alafenamide Fumarate or ABACavir in patients with Tenofovir Disoproxil Fumarate associated eGFR decline. A randomized clinical trial. - BACTAF
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- Erasmus MC
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •18 years or older
- •HIV-positive with HIV-RNA <50 c/ml for at least 6 months
- •Stable on TDF/FTC or TDF/3TC for at least 12 months, in combination with a 3rd antiretroviral agent
- •Confirmed/probable TDF-related eGFR-decline with absence of other causes of eGFR-decline.
- •HLA-B5701 allele negative
- •General medication and condition does not interfere with trial procedure.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 80
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Chronic hepatitis B or C
- •Symptomatic arterial disease e.g. a history of coronary artery disease, ischemic cerebrovascular accident or claudication intermittens in medical history
- •Not meeting all inclusion-criteria as mentioned above
研究者
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