Epithelioid Hemangioma of Bone And Soft Tissue: a Benign Tumor With Metastatic Potential
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 主要终点
- Multifocal presentation of patients with epithelioid hemangioma of bone and soft tissue without producing a fatal outcome
研究概览
简要总结
The controversy surrounding epithelioid hemangioma diagnosis stems from its somewhat aggressive clinical characteristics, including multifocal presentation and occasional lymph node involvement.
The investigators reviewed the clinicopathologic and radiologic characteristics of bone and soft tissue epithelioid hemangioma in patients treated at our institution with available tissue for molecular testing.
The hypothesis is that epithelioid hemangioma may present with multifocal involvement and rare loco-regional lymph node metastasis, but it remains a benign tumor with excellent prognosis.
详细描述
The investigators retrospectively reviewed patients treated for epithelioid hemangioma of the bone and soft tissue in a single insitution. The purpose of this study is to evaluate the pathological, clinical, and radiological characteristics of epithelioid hemangioma arising within bone and soft tissue, in the first cohort of cases where the definitive diagnosis is supplemented by molecular techniques.
The hypothesis is that the improved knowledge regarding this rare entity can more definitively elucidate the benign biology of epithelioid hemangioma.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with epithelioid hemangioma of bone and soft tissue in the extremities and pelvis
排除标准
- •patients with epithelioid hemangioma of bone and soft tissue in the spine
结局指标
主要结局
Multifocal presentation of patients with epithelioid hemangioma of bone and soft tissue without producing a fatal outcome
时间窗: 2 years
The investigators defined multifocal presentation the presence of secondary lesions by imaging at presentation of the disease or during follow-up.
次要结局
未报告次要终点
研究者
Costantino Errani
MD, PhD.
Istituto Ortopedico Rizzoli