Assessment of Thyroid Hormone Levels and Potential Risk of Hypothyroidism in Healthcare Workers Exposed to Low-dose Ionizing Radiation
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- thyroid function assessment
研究概览
简要总结
"This study is designed to evaluate the thyroid health of healthcare workers exposed to low-dose ionizing radiation at INMOL Cancer Hospital, Lahore. Specifically, it investigates whether prolonged occupational exposure in radiology and nuclear medicine departments is associated with altered thyroid hormone levels or an increased risk of hypothyroidism. The thyroid gland is highly sensitive to radiation, and existing literature suggests a possible link between occupational exposure and thyroid dysfunction.
详细描述
A cross-sectional research design will be used over a four-month period. A sample of 44 participants will be selected using purposive sampling from the hospital's radiology and nuclear medicine staff.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Staff members from radiology and nuclear medicine departments who meet both conditions.
- •workplace experience exceeding one year
- •age between 20 to 40 will be selected for this study.
排除标准
- •Employees who have worked less than twelve months
- •pregnant participants.
结局指标
主要结局
thyroid function assessment
时间窗: 12 Months
Thyroid function is assessed through blood tests, primarily measuring TSH (Thyroid Stimulating Hormone), T4 (Thyroxine), and sometimes T3 (Triiodothyronine) levels. Abnormal levels of these hormones can indicate an underactive (hypothyroidism) or overactive (hyperthyroidism) thyroid. Normal Ranges (approximate): TSH: 0.4 - 4.0 mIU/L Free T4: 0.7 - 1.9 ng/dL Total T4: 5.0 - 12.0 μg/dL Total T3: 80 - 220 ng/dL
次要结局
未报告次要终点
研究者
Muhammad Naveed Babur
Principal Investigator
Superior University