Viral and Host Factors in the Transmission and Pathogenesis of HIV
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 600
- 试验地点
- 2
- 主要终点
- Participants are tested for HIV-1 RNA levels, the presence of antibodies to HIV antigens, and T cell subsets
研究概览
简要总结
To study the collection of blood from individuals known to be at high risk for HIV-infection or who have been recently infected with HIV.
The data collected are used for diagnostic, prognostic and management decisions as outlined by current HIV-1 Treatment Guidelines.
详细描述
This phlebotomy protocol permits the collection of blood from individuals known to be at high risk for HIV-infection or who have been recently infected with HIV.
Participants will have from 10 to 60 ml (approximately 1 to 4 tablespoons) of blood drawn for one or all of the following tests:
- T cell subset enumeration
- Serologic reactivity with HIV antigens
- Viral load assays by bDNA, PCR, or RT-PCR
- Routine Laboratory assessments (chemistries, liver function tests, hepatitis serology, RPR)
- HIV-1 Resistance Testing
These data are used for diagnostic, prognostic and management decisions as outlined by current HIV-1 Treatment Guidelines
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •recently infected with HIV-1 HIV-1 negative, and at high risk for infection
排除标准
- 未提供
结局指标
主要结局
Participants are tested for HIV-1 RNA levels, the presence of antibodies to HIV antigens, and T cell subsets
时间窗: first visit
次要结局
- Data will be used for diagnostic, prognostic and management decisions as outlined by current HIV-1 Treatment(first visit)