Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 5,084
- 试验地点
- 1
- 主要终点
- Prevalence of diabetes foot complications: hyperkeratosis
研究概览
简要总结
The study aims to assess foot complications among patients with diabetes in Canada, using patient data collected during diabetes foot assessments performed by the LMC Chiropody Team between February 27, 2018 and April 17, 2019.
详细描述
Among patients with diabetes, one of the major causes of increased morbidity and mortality include lower-extremity complications. Patients who have peripheral neuropathy and peripheral arterial disease are at risk of developing foot ulcers and infection, which can lead to lower-extremity amputations. Adults with diabetes in Canada are 20 times more likely to be hospitalized for a nontraumatic lower limb amputation than adults without diabetes. Thus, the prevention, education and early treatment of diabetes foot complications are an important component of caring for patients living with diabetes.
In addition to neuropathy and peripheral arterial disease, risk factors for developing foot ulcers include increased levels of glycated hemoglobin, onychomycosis, microvascular complications, previous foot ulcer or amputation, structural deformity, and limited joint mobility. To the best of our knowledge, the prevalence of foot complications, such as onychomycosis, and the association of diabetes foot complications with glycemic control and other diabetes risk factors, has not been assessed before in a large sample of Canadian patients. To better understand foot complications among patients with diabetes in Canada, the investigators will retrospectively examine patient data collected during diabetes foot assessments performed by the LMC Chiropody Team. The LMC Chiropody Team is part of LMC Diabetes & Endocrinology, which is one of the largest endocrine practice groups globally.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years
- •Diagnosis of type 1 or type 2 diabetes
- •Under the care of an endocrinologist at LMC
- •Diabetes foot assessment was performed by the LMC Chiropody Team
- •Informed consent to use patient medical record data for research purposes was provided
排除标准
- •Prior diabetes foot assessment by an LMC chiropodist
结局指标
主要结局
Prevalence of diabetes foot complications: hyperkeratosis
时间窗: 24-hours
Proportion of patients with hyperkeratosis
Prevalence of diabetes foot complications: onychauxis
时间窗: 24-hours
Proportion of patients with onychauxis
Prevalence of diabetes foot complications: foot deformities
时间窗: 24-hours
Proportion of patients with foot deformities
Prevalence of diabetes foot complications: foot ulcer
时间窗: 24-hours
Proportion of patients diagnosed with a foot ulcer
Prevalence of diabetes foot complications: onychocryptosis
时间窗: 24-hours
Proportion of patients with onychocryptosis
Prevalence of diabetes foot complications: onychomycosis
时间窗: 24-hours
Proportion of patients with onychomycosis
Prevalence of diabetes foot complications: neuropathy risk
时间窗: 24-hours
Risk for neuropathy will be measured using the modified Toronto Clinical Neuropathy Score (mTCNS)
次要结局
- Association between foot risk variables and the presence of a foot ulcer(24-hours)
- Diabetes foot assessment risk group(24-hours)
