The Effects of Mat Pilates Training on Vascular Function in Obese Premenopausal Women With Elevated Blood Pressure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 2
- 主要终点
- Arterial Stiffness
研究概览
简要总结
Obesity is associated with progressive decreases in arterial health and function. It is crucial to prevent or reduce the negative effects of aging on the vasculature by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a Mat Pilates training (MPT) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx) and endothelial function in obese premenopausal women with elevated BP.
详细描述
Using a parallel experimental design, participants were randomly assigned to either MPT (n=14) or non-exercising control group (n=14) for 12 weeks. Participant in the MPT group trained 3 days/week . Participants' brachial to ankle PWV (baPWV), systolic and diastolic BP, AIx, plasma NO levels were measured at baseline and after 20 weeks of their assigned intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •body mass index 30-40 kg/m2
- •<1 h of regular exercise per week in the previous year
- •systolic/diastolic BP: 120-129mm Hg systolic BP and ˂ 80 mm Hg for diastolic BP
- •Nonsmokers
排除标准
- •body mass index ˂30 and ≥40 kg/m2
- •chronic diseases
- •taking oral contraceptives
- •pregnancy
结局指标
主要结局
Arterial Stiffness
时间窗: 12 weeks
via Pulse Wave Velocity
次要结局
- Pressure Wave Reflection(12 weeks)
- Endothelial Function(12 weeks)
- Systolic and Diastolic Blood Pressure(12 weeks)
研究者
Alexei Wong
Assistant Professor
Marymount University