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临床试验/NCT03279991
NCT03279991已完成不适用

Neuromed- Integrated Health Life Platform and Biobank

Neuromed IRCCS1 个研究点 分布在 1 个国家目标入组 4,000 人开始时间: 2019年3月4日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
4,000
试验地点
1
主要终点
Biological sample bank

研究概览

简要总结

This project aims to create a digital platform for personal, clinical, diagnostic and environmental data collection, management and analysis of patients with cardiovascular and neurological disease or cancer admitted to the Neuromed Group clinics, associated with a biobanks of biological fluids and human tissues and a biotechnological platform for "omics" analysis, to encourage personalized, preventative and predictive care.

详细描述

There is a need for a change of vision in health care that could become a key innovation point for digital medicine in the future, a sort of Copernican revolution: the starting point is no longer the disease, but the patient around whom pathologies and risk factors rotate, not as distinct and uniquely defined entities, but as communicating and interconnected possibilities that define their form only in relation to the individual, his genome, his personality, his habits of life and the environment in which he lives. From these interactions, a personalized, dynamic, integrated, and continuous diagnostic and therapeutic pathway is created that accompanies the person not only in the stage of the disease but also in the previous and subsequent phases, becoming a way of life oriented towards the health of the person rather than a way to cure a disease.

An Integrated Health Life Platform enables you to develop an interactive healthcare health model among all actors who manage the health of the person, healthcare professionals in the area, and hospitals, caregivers, and community through the integration of remote monitoring of data with A virtual community.

The platform is thought not as a pure aggregation of data, but as a digital hub centered on the patient, with his (clinical and personal) data, but also the environment in which he lives, his behaviors, accessibility to services and The relationships that come to them and from them. The platform aims to effectively integrate self management, personalization of the path, and co-production of health, demonstrating that these three key dimensions of care are mutually reinforcing.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
19 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Men and women
  • Older than 18 years
  • Cardiovascular disease
  • neurodegenerative disease
  • Pregnancy

排除标准

  • Inability to understand and to want
  • Refusal to sign the informed consent

结局指标

主要结局

Biological sample bank

时间窗: baseline

A repository of biological samples, "Neurobiobank", from patients who will join the project, will be organised at the biotechnology park of Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Neuromed of Pozzilli under the responsibility of the experienced staff at the Department of Epidemiology and Prevention.

omics analysis

时间窗: baseline

Measure of genomic, epigenetic and proteomic fingerprint of recruited patients

Four P (4P) medicine

时间窗: Baseline

Identification of patterns within the health data that correlate with disease or wellness and create personalised pathway of prevention and care.

Integrated health-life big data platform

时间窗: baseline

Analytical tools will be developped for integrating structured and unstructured patients data sets and derive actionable information from their observed interrelationships.

次要结局

未报告次要终点

研究者

发起方
Neuromed IRCCS
申办方类型
Other
责任方
Principal Investigator
主要研究者

Licia Iacoviello

Professor

Neuromed IRCCS

研究点 (1)

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