The Rates of Overtreatment and Deintensification of Antidiabetic and Antihypertensive Medications in Patients With Diabetes Mellitus
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,276
- 试验地点
- 1
- 主要终点
- Overtreatment for glycemia
研究概览
简要总结
This study evaluates the overtreatment and deintensification rates of antidiabetic and antihypertensive medications in patients with diabetes mellitus in Turkey.
详细描述
Diabetes mellitus is one of the most common chronic diseases which lead to serious public health problems and a significant economic burden worldwide. The prevalence of diabetes in elderly patients is very high and is predicted to increase dramatically.
Prior studies have generally been concerned with the inadequate treatment of diabetes however, over the last few years the overtreatment of diabetes has also come to the fore. Unfortunately, there are very few data worldwide and no data in Turkey about the overtreatment of patients with type 2 diabetes.
This study aimed to assess the rates and predictors of overtreatment and undertreatment of glycemia and blood pressure in older adults with T2DM. Treatment deintensification or intensification by the physicians were also investigated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with Diabetes Mellitus type I or II
- •Age 65 years or older
- •To be under follow-up in the same center for at least one year.
排除标准
- •Younger than 65 years old
- •having decompensated liver disease
- •psychiatric disorders interfering cognition or compliance
- •having bariatric surgery or on renal replacement therapy
结局指标
主要结局
Overtreatment for glycemia
时间窗: 7 days
HbA1c\<6.5% plus use of ≥2 oral hypoglycemics or insulin, except metformine.
次要结局
- Undertreatment for blood pressure(7 days)
- Overtreatment for blood pressure(7 days)
- Deintensification of treatment(7 days)
- Undertreatment for glycemia(7 days)
研究者
Alper Sonmez
Prof. Dr.
Gulhane School of Medicine