CTRI/2018/05/013917进行中（未招募）2 期
A Randomized prospective study comparing Neoadjuvant treatment Response in Rectal Cancer, Short Course Radiotherapy followed by Chemotherapy versus Conventional Chemo-radiation: A North East India Based Tertiary Care Hospital Experience
Shashank Bansal0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Age >= 18 years and < 70 years
- •ECOG performance score <= 1
- •Written informed consent
- •Biopsy proven rectal adenocarcinoma
- •Metastatic lateral lymphnodes (LN+)
- •Involved mesorectal fascia (MRF+)
- •Locally advanced tumour fulfilling at least one of the following criteria on pelvic MRI:
- •cT2 ,cT3,cT4a
- •Creatinine levels indicating renal clearance >= 50 ml/min
- •Bilirubin < 35 μmol/L
排除标准
- •Tumour involving lumbosacral nerve roots
- •Distant metastasis (M1)
- •Recurrent rectal cancer
- •FAP or HNPCC, Active Chrons disease
- •Contraindications to MRI (e.g. pacemaker)
- •Myocardial infarction within past 12 months or clinically significant cardiac disease
- •Inability to give informed consent
- •Concomitant malignancies
研究者
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