NCT04684004已完成不适用
Blood Glucose Values at Hospital Admission and Clinical Outcomes in Patients With Takotsubo Syndrome: Hyperglycemia Effects on Heart Failure Events and Mortality at 24 Months of Follow-up
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- The number of HF events
研究概览
简要总结
Patients with Takotsubo cardiomiopathy (TTC) have over-inflammation and over-sympathetic tone. However, these conditions could cause higher rate of heart failure (HF) events and deaths at 2 years of follow-up. Conversely, hyperglycemia vs. normoglycemia could result in over expression of inflammatory markers and catecholamines thta could result in higher rate of HF and deaths at 2 years of follow-up in TTC patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •acute onset of a cardiovascular event, usually associated with substernal chest pain, initially regarded as STEMI/evolving coronary syndrome;
- •cardiac biomarker modifications (creatine kinase-MB and troponin I);
- •systolic dysfunction, predominantly characterized by akinesia/hypokinesia of the mid-to-distal portion of the left ventricle (LV) chamber, with hyper-contractile basal LV.
排除标准
- •patients with previous previous myocardial infarction;
- •patients with previous TTC event;
- •patients affected by chronic kidney, liver, and cerebrovascular diseases.
结局指标
主要结局
The number of HF events
时间窗: 12 months
To evaluate the number of HF events by clinical visits, telephonic interviews and hospital discharge schedules.
次要结局
未报告次要终点
研究者
Celestino Sardu
researcher
University of Campania "Luigi Vanvitelli"
研究点 (1)
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