Role of individualized homoeopathic medicine in 50 millesimal scale in management of ganglion cyst of hand and open single arm pre and post clinical trial

This prospective, open-label, single-arm pre-post clinical trial will be conducted over 18 months at the National Institute of Homoeopathy, Kolkata, with each patient followed for six months. The study aims to evaluate the effectiveness of individualized homoeopathic medicine in management of ganglion cyst of hand. This study aims to assess changes in Ganglion cysts of the hand using the Patient-Rated Wrist/Hand Evaluation Score and pain levels via the Visual Analogue Scale (VAS). It also evaluates overall well-being through the Modified Naranjo Criteria, determines the prevalence of Ganglion cysts based on age, sex, socio-economic status, and occupation among NIH OPD/IPD patients, and identifies the most frequently indicated homoeopathic medicines along with their miasmatic background for effective management. Adults aged 05-65 years suffering from ganglion cysts of hand, fluent in English, Hindi, or Bengali, and willing to provide consent will be included. Exclusion criteria include cases requiring immediate surgery or life support, those with uncontrolled systemic illness, life-threatening infections, or organ failure, unstable psychiatric conditions, pregnant or lactating women, substance abuse or dependence, self-reported immunocompromised state, and patients under homeopathic treatment for chronic disease within the last three months or unwilling to give consent. Individualized homeopathic remedies will be selected based on repertorization (RADAR OPUS) and Materia Medica, following Hahnemannian principles, with monthly follow-ups for six months to assess symptom changes. The outcome assessment of the patients shall be calculated as per changes in and applying the core interpretation of Patient Rated Hand/ Wrist Evaluation (PRHWE) Score, Visual analogue scale (VAS) and Modified Naranjo Criteria at baseline and after 6 months.