Effects of Cord Blood 25-hydroxy-vitamin D Level on Early Neonatal Morbidities
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 主要终点
- sepsis
研究概览
简要总结
Cholecalciferol (vitamin D3) is a prohormone and its active form is 1,25 dihydroxycholecalciferol. This hormone has effect on both calcium, phosphorus and bone metabolism and also bone morrow, muscle, heart and immune system. For a long time, maternal low vitamin D level is a well known problem for our country and the level was reported as <10 ng/ml for 46-80% of mothers.The most prominent risk factor was determined as low socioeconomic status. Therefore, the level of 25-hydroxy-vitamin D is supposed to be in relation with several neonatal morbidities and maternal complications of pregnancy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 30 Minutes（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Term or preterm newborns which are hospitalized in the Neonatal Intensive Care Unit of our hospital
排除标准
- •Preterm babies born before the
- •gestational week
- •Babies with complex cardiac anomalies and/or dysmorphic features
结局指标
主要结局
sepsis
时间窗: 3 months but patients will be followed until discharge
hypocalcemia
时间窗: 3 months but patients will be followed until discharge
feeding intolerance
时间窗: 3 months but patients will be followed until discharge
bronchopulmonary dysplasia
时间窗: 3 months but patients will be followed until discharge
patent ductus arteriosis
时间窗: 3 months but patients will be followed until discharge
retinopathy of prematurity
时间窗: 3 months but patients will be followed until discharge
maternal complications of pregnancy
时间窗: from the beginning of gestation until birth process
次要结局
- rachitism(4 months but patients will be followed until discharge)
研究者
birgul say
Fellow in Neonatology, Pediatrician
Zekai Tahir Burak Women's Health Research and Education Hospital