â€œA comparative clinical study to assess the role of Pachan given by Paniya Kshar and by Panchakol Churn on the efficacy of Virechana Karma in Yuvanpidika. â€

National Institute Of Ayurveda1 个研究点分布在 1 个国家目标入组 30 人开始时间: 2023年10月1日最近更新: 2024年9月3日

试验速览

阶段: 2/3 期
状态: 已完成
发起方: National Institute Of Ayurveda
入组人数: 30
试验地点: 1
主要终点: Right cheek 2

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Acne vulgaris is a chronic inflammatory disease of the pilosebaceous follicles chracterised by comedons, papules,pustules and often scars. Chiefly on cheeks, chin, nose, forehead and upper trunk. Acne tends to appear earlier in female, due to later onset of puberty in males.

In Ayurvediya samhitas, there is a brief description available about Yuvanpidika. Which is a type of Khudraroga. The early first description of Yuvanpidika is given in Sushrut samhita. In Charak samhita it is not describe as separate Vyadhi but in â€˜Tristreshniya adhayayaâ€™ Pidika roga is said to occur as Bahya roga marga ashrita roga (ch.su. 11/47) . Yuvanpidika is described by Acharya Sushruta as a separate vyadhi in Nidan sthan 13 and Chikitsa sthan 20 under Khudra rogas. Likewise Acharya Madhav and Acharya Vagbhatt have described Yuvanpidika under Khudrarogas and not in separate chapter*. Acharya* Sushrut has mentioned 44*, Acharya Vagbhatt* 36, and Acharya Madhav has quoted 43 Khudra rogas.

Acharya Vagbhatt mentions the involvement of Vata, Kapha and Meda in the development of Yuvanpidika. The involvement of Meda can be considered to show similarity with the involvement of sebum in acne. In Samhita various treatment of Yuvanpidika has been described but all can be concluded in two groups :-

1.Shodhan chikitsa- That is purification of body it includes Vaman,Virechana,

Nasya Karm and Raktmokshana.

2.Saman chikitsa- That is conservative treatment by oral and tropical medicines. It includes Lepa, Upnaha and Kshar Karm.

WORK PLAN: -

A. GROUPING- After the complete examination and investigation, all the 30 patients will be randomly divided into two groups equally (15 patients in each group) as below

GROUP-A

1. Pachan with Paniya kshar (Apamarg kshar in 1 gm in 36ml water) dose for initial 5 days in the morning )

2. Mix Apamarg kshar(1gm) in Goghrit for Snehapan(starting dose 25 ml) in increasing dose till the occurance of Samyak Snehan lakshan

3. Sarvang Abhayang & Swedan Will be done on 2nd ,3rd ,4th 5th day of Samyak Snehan and on the day of Virechana.

4. Virechana with Trivritavleha

. (dose 40-60gm)

5. Sansarjana Karma according to Shudhi Lakshan.

GROUP-B

1.Pachan with Panchakol churn (3gm) with lukewarm water For initial 5 days in the morning.

2. Snehapan with Goghrit (starting dose 25 ml) in increasing dose till the occurance of Samyak Snehan lakshan (no any Parkshep dravya added)

3. Sarvang Abhayang & Swedan Will be done on 2nd ,3rd ,4th 5th day of Samyak Snehan and on the day of Virechana.

4. Virechana with Trivritavleha

(dose 40-60gm)

5.Samsarjana Karma

研究设计

研究类型: Interventional
分配方式: Computer generated randomization
盲法: Open Label

入排标准

年龄范围: 18.00 Year(s) 至 40.00 Year(s)（—）
性别: All

入选标准

•Patients with cardinal symptoms of Yuvanpidika like:- Shalmli kantak aakar pidika, Ruja Yukta , Ghanta, Medogarbhata, toda ,srava.
•Patients between 18-40 years of age group, irrespective of gender and religion.
•Individual with mild to moderate symptoms of Aam.
•4.Patient who are indicated for Virechana Karma.

排除标准

•Patients presenting with any serious disease having gross electrolyte imbalance and low BT/CT value.
•Patients who are unwilling for Virechana Karma.
•Patient with any systemic disorders like Cardiac problem,Diabetes mellitus, Hypertension, Fever etc.