Negative Oral Contrast Agents Utilization in PET/CT Studies
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- compare the performance of different negative oral contrast agents in PET/Ct studies
研究概览
简要总结
To compare the performance of different negative oral contrast agents in bowel distension in patient referred for PET/CT studies for various causes aiming for identification of ideal oral contrast agent(OCA).
详细描述
Evaluation of gastrointestinal pathology depends on adequate bowel distention, which optimizes resolution of the bowel wall and contents. Traditionally, high-attenuation oral Contrast material in the form of iodine solutions or barium suspensions has been used to obtain bowel distension in MDCT examinations
Traditional high-contrast oral agents like iodine solutions, and barium suspensions which due to overcorrection problems in PET-CT interpretation lowers the accuracy of diagnosis. Negative oral contrast agents like water, air, fat containing agents used with 12.5% corn oil and polyethylene glycol has been used in radiological studies. Milk with 4% fat content has also been tested out in radiological studies and found to be effective. As it is more easily available, palatable, and acceptable especially, by children it needed to be tested in the visualization of the GIT in the PET-CT studies compared to other negative contrast agents.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patients referred to our unit for PET/CT study for various causes
排除标准
- •Patients with GIT disease.
- •Pregnancy and lactation.
- •Severely ill patients.
结局指标
主要结局
compare the performance of different negative oral contrast agents in PET/Ct studies
时间窗: baseline
comparing the effect of different oral contrast on bowel distention
次要结局
未报告次要终点
研究者
Nahla Mostafa Mahmoud Bashank
PhD
Assiut University