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临床试验/NCT07298668
NCT07298668尚未招募不适用

Standard Modifiable Risk Factors in Middle Eastern Patients With Stroke (Jo-SMMART Study)

Jordan Collaborating Cardiology Group1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2025年12月31日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
2,000
试验地点
1
主要终点
Prevalence of current cigarette smoking in stroke patients (survey interview)

研究概览

简要总结

Stroke is a well-known a leading cause of death and disability in the Middle East. There remain many knowledge gaps in evaluating the prevalence of risk factors among patients with stroke in the Middle East. Unravelling the impact of these risk factors and controlling them can positively lower the incidence of stroke. Disparities in stroke risk factors, may well be related to ethnicity of the Middle Eastern populations , will be compared with those among stroke patients in the western literature.

详细描述

Stroke is a well-known a leading cause of death and disability in the Middle East. There remain many knowledge gaps in evaluating the prevalence of risk factors among patients with stroke in the Middle East. Unravelling the impact of these risk factors and controlling them can positively lower the incidence of stroke. Disparities in stroke risk factors, may well be related to ethnicity of the Middle Eastern populations , will be compared with those among stroke patients in the western literature.

These clinically relevant issues have not been studied extensively in the Middle East where most of the studies in atherosclerotic cardiovascular disease have focused on acute coronary syndrome more than stroke. Exploring new information on risk factors of stroke in this region that helps fill some of the knowledge gaps.

Stroke has been attributed, in the majority of cases, to the traditional four standard modifiable risk factors of hypertension, type 2 diabetes, dyslipidemia, and cigarette smoking. However, ethnicity and geography account for the interregional differences of the prevalence of risk factors in patients with stroke.

The Jo-SMMART ill evaluate risk factors in 2000 stroke patients in Jordan as a representative of the Middle Eastern population, the prevalence of those with none of the 4 risk factors and the differences in clinical profiles and demographic features on those with risk factors and those with no risk factors. Lipid profile and use of lipid lowering agents will also be evaluated, and furthermore the die0fferneces between young vs old, and men vs women stroke patients ill be addressed.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of stroke upon admission to the hospital
  • Adult aged 18 years or older
  • Available lipid profile on hospital admission

排除标准

  • Stroke diagnosis unconfirmed
  • age younger than 18 years
  • No available lipid profile on admission

结局指标

主要结局

Prevalence of current cigarette smoking in stroke patients (survey interview)

时间窗: BASELINE

Known current cigarette smoking of any number of cigarettes per day

Prevalence of hypertension in stroke patients (survey interview)

时间窗: Baseline

BP more 140/90 or known diagnosis of high blood pressure or patient already on blood pressure medication

Prevalence of type 2 diabetes in stroke patients (survey interview)

时间窗: BASELINE

HbA1c more than 6.5%, or known diagnosis of type 2 diabetes or patient already on anti diabetes medications

Use of lipid lowering therapy (survey interview)

时间窗: BASELINE

Current use of statin, ezitimibe, PCS9 inhibitor of small interfering RNA agent to lower the LDL-C

Prevalence of elevated serum level of low density lipoprotein cholesterol in stroke patients (survey interview)

时间窗: BASELINE

Elevated serum level of low density lipoprotein cholesterol \> 55 mg/dl or patient already on lipid lowering medication

次要结局

未报告次要终点

研究者

发起方
Jordan Collaborating Cardiology Group
申办方类型
Other
责任方
Sponsor

研究点 (1)

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