Effects of pioglitazone or metformin on bone markers and bone mineral density as well as parameters of atherosclerosis in patients with type 2 diabetes - Effects of pioglitazone or metformin on bone metabolism and atherosclerosis

Department of Internal Medicine 1, Shimane University School of Medicine0 个研究点目标入组 60 人开始时间: 2009年5月22日最近更新: 2023年10月17日

适应症

试验速览

阶段: 未知
状态: 已完成
发起方
入组人数: 60

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

In the pioglitazone group bone mineral density at femoral neck and radius were significantly decreased, whereas the parameters of atherosclerosis were not changed. On the other hand, in the metformin group bone mineral density was not changed, whereas the parameters of atherosclerosis were significantly increased.

研究设计

研究类型: Interventional

入排标准

年龄范围: ot applicable 至 ot applicable（—）
性别: All

入选标准

未提供

排除标准

•Nobody had hepatic or renal dysfunction or nutritional derangements. Patients treated with TZDs and metformin were excluded from this study. All patients were free of drugs known to influence bone and calcium metabolism, such as vitamin D, bisphosphonate, or estrogen, up until the time of the study.

研究者

发起方

Department of Internal Medicine 1, Shimane University School of Medicine

相似试验

已完成

不适用

Effects of pioglitazone on bone formation and resorption markers in type 2 diabetes mellitus.

JPRN-UMIN000023805niversity of Occupational and Environmental Health, Japan60

已完成

2 期

Effect of Pioglitazone Versus Metformin on Bone Health in Postmenopausal Women With Type 2 DiabetesGlucose Metabolism DisordersDiabetes Mellitus, Type 2Diabetes Mellitus

NCT01935804King Abdulaziz University440

已完成

2 期

Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic PeriodontitisChronic Periodontitis

NCT03204058Government Dental College and Research Institute, Bangalore90

已完成

2 期

Locally Delivered Metformin and Aloe Vera for Treatment of Intrabody Defects in Chronic PeriodontitisChronic Periodontitis

NCT03204071Government Dental College and Research Institute, Bangalore90

已完成

不适用

Pioglitazone and Lumbar Bone Marrow Fat in Chronic Kidney DiseasePolycystic Kidney Diseases

NCT02739750Indiana University35