EUCTR2004-004403-37-DE进行中（未招募）1 期
Eine monozentrische, randomisierte, kontrollierte Studie zur Untersuchung von Interferon-beta zur Behandlung der Multiplen-Sklerose (MS)-assoziierten und primären Uveitis intermedia im Vergleich zur StandardtherapieA monocentric, randomised, controlled trial for the investigation of Interferon-beta in the treatment of multiple-slerosis (MS)-associated and primary uveitis intermedia compared to the standardized treatment - TEAM-Studie
niversitätsklinikum Heidelberg0 个研究点目标入组 34 人开始时间: 2005年10月28日最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 34
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- male and female patients who are at least 18 years old
- •- active, one or two-sided non-infectious uveitis intermedia for at least one year
- •- visual acuity ranging from at least 0,1 up to 0,6 on the worse eye, due to a macula edema (height of fovea > 180 micrometers)
- •- multiple sclerosis (if there is no primary uveitis intermedia)
- •- previous therapy with corticosteroids for a minimum of 4 weeks with at least 0,5 mg/kg body weight which has not been successful
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- a sole uveitis anterior
- •- no macula-edema
- •- an atrophy of the optic nerve after retro-bulbar-neuritis
- •- a peri- or intraocular injection of corticosteroids in the last 3 months
- •- a prior, unsuccesful, systemic treatment with prednisone
- •- a prior, unsuccesful, systemic treatment with acetacolamid (in order to treat macula edema)
- •- a known allergy against human or recombinant Interferon
- •- a psychiatric diagnosed endogenous depression
- •- diseases of the liver for which hepatotoxic pharmaceuticals cannot be tolerated
- •- infectious kinds of uveitis
- •- all systemic diseases except for MS
- •- pregnancy, lactation
- •- no contraception
- •- additional metabolic or psychiatric diseases or malignant tumor(s)
研究者
相似试验
进行中（未招募）
1 期
Eine multizentrische, randomisierte, kontrollierte Studie zur Untersuchung von Adalimumab bei der Behandlung verschiedener Formen von refraktärer Uveitis im Vergleich zur StandardtherapieRandomized controlled study to evaluate the efficacy of Adalimumab in patients with different forms of refractory UveitisEUCTR2006-001732-53-DEniversity Hospital of Heidelberg
已完成
不适用
Comparison of two devices for breathing support in newborn babiesPremature birthTransient tachypnea of the newbornACTRN12619000535178Fisher & Paykel Healthcare10
进行中（未招募）
不适用
A single-center, randomized, controlled, observer-blind, phase IV study to develop the atopic localized eczema regression test (ALERT) using marketed topical corticosteroid formulations of different strength and the calcineurin inhibitors pimecrolimus (Elidel®) in patients with a pre-disposition for atopic dermatitis - Atopic localized eczema regression test (ALERT)Patients with a pre-disposition for Atopic DermatitisEUCTR2009-012194-35-DEbioskin GmbH
已完成
不适用
A single center, randomized, open-label, controlled, three-arm study to evaluate the effect of a new combined oral contraceptive (COC) containing 15 mg Estetrol (E4) and 3 mg Drospirenone (DRSP) and of two reference COCs containing either 30 mcg Ethinylestradiol (EE) and 150 mcg Levonorgestrel (LNG) or 20 mcg EE and 3 mg DRSP on endocrine function, metabolic control and hemostasis during 6 treatment cyclesContraceptionbirth controlNL-OMON43221Estetra SPR100
进行中（未招募）
不适用
A single-center, open-label, controlled, randomized study to investigate the impact of a sequential oral contraceptive containing estradiol valerate and dienogest (SH T00658ID) as compared to a sequential oral contraceptive containing ethinylestradiol and levonorgestrel (SH D00264A) on plasma lipids, hemostatic variables, and carbohydrate metabolism in 60 healthy female volunteers aged 18-50 years over 7 treatment cycles - Metabolism study vs Triquilar 21+7ContraceptionEUCTR2004-001614-13-DESchering AG60