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临床试验/NCT05132036
NCT05132036已完成不适用

Lung Ultrasound Assessment of Fluid Overload in Haemodialysis Patients Using 8 Sites Score

Centre Hospitalier Universitaire, Amiens2 个研究点 分布在 1 个国家目标入组 46 人开始时间: 2021年11月9日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
46
试验地点
2
主要终点
number of patients with fluid overload

研究概览

简要总结

Determination of the hemodialysis ultrafiltration volume is guided by the clinician's estimate of dry weight. A poor estimate of this dry weight may result in insufficient fluid depletion causing a state of volume overload, which may be associated with long-term left ventricular failure, high blood pressure and excess of mortality. The diagnosis of fluid overload in haemodialysis patient is routinely based on clinical examination which consists of cardiopulmonary auscultation and edema palpation of limb member. Clinical examination can be completed by paraclinical examinations, and bioimpedance is an objective tool that assess fluid overload state. This test provides an individualized hydration status and fluid overload based on normal extracellular volume considering body composition. Echocardiography allows an accurate assessment of blood volume status by simultaneous studying left ventricular filling pressures, systolic pulmonary artery pressure and the diameter of the inferior vena cava. Lung ultrasound analyses the B-lines defined as artefactual images resulting from contact between air in "alveoli" and water in "septa". It can estimate pulmonary congestion. The aim of the study is to evaluate the lung ultrasound using "8 sites" score accuracy for estimating fluid overload of patients before hemodialysis session.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age over 18 years old
  • patients on hemodialysis for more than 3 months;
  • patients without cardiological or infectious event for at least 3 months;
  • patients having at least 2 dialysis session per week;
  • patients affiliated with a health insurance plan;
  • patients having signed an informed consent.

排除标准

  • Pulmonary fibrosis or active lung disease;
  • residual diuresis over 500 mL per day;
  • body mass index (BMI) < 21 and > 28 Kg/m²;
  • medical history of major amputation (subgonal or transfemoral);
  • pacemaker carrier;
  • patients with orthopedic prosthesis.

结局指标

主要结局

number of patients with fluid overload

时间窗: one day

Fluid overloaded are determined by both tecniques : estimated fluid overload and lung ultrasound measured fluid overload

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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