NCT01762098已完成不适用
Prevalence of Chronic Endometritis in Patients With Recurrent Miscarriages or Repeated Implantation Failures in In-vitro Fertilization
Clinique Ovo1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2012年11月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Rate of chronic endometritis
研究概览
简要总结
Chronic endometritis is a persistent inflammation of the endometrium. Chronic endometritis is asymptomatic or little symptomatic. Sometimes, patient with chronic endometritis can have genital bleeding, pelvic chronic pain, pain during sexual relations, persistent vaginal white loosing. The hysteroscopy can detect the presence or absence of chronic endometritis.
Some studies showed that the endometritis could have an impact on the embryo implantation and could explain recurrent miscarriages or repeated embryo implantation failures.
The goal of this study is to evaluate the frequency of the chronic endometritis in patients with recurrent miscarriages or repeated embryo implantation failures
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Group repeated miscarriages
- •Women aged 18 to 43 years
- •≥ 2 miscarriages before 14 weeks of gestation
- •Genetic (karyotype x2), thrombophilic and endocrine assessment should be completed
- •Group of implantation failure in In-vitro fertilization
- •Women aged 18 to 45 years
- •Absence of pregnancy after 3 good quality embryos transferred in women under 35 years and 4 embryos in the 35 years and over.
排除标准
- •Positive pregnancy test
- •Unexplained bleeding
- •Incomplete miscarriage assessment
- •Uterine malformation
- •Antibiotic treatment during or within one month prior to the biopsy
结局指标
主要结局
Rate of chronic endometritis
时间窗: 1 day
次要结局
- Pregnancy rate(1 year)
研究者
研究点 (1)
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