Randomized double-blind comparison of phenylephrine and norepinephrine for treatment of post-spinal hypotension in parturients with fetal compromise

niversity College of Medical Sciences and Guru Teg Bahadur Hospital0 个研究点目标入组 100 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1. Healthy females with singleton pregnancy undergoing emergency caesarean section for potential fetal compromise under spinal anaesthesia
•2. Non-reassuring fetal heart rate (FHR) status i.e. FHR more than 160 or less than 100 bpm
•3. FHR deceleration(variable or late), which fails to recover after uterine contraction has passed (type 2 dips)
•4. Meconium stained liquor with FHR abnormality or thick meconium stained liquor
•5. Cord prolapse
•6. Intra-uterine growth restriction
•7. Oligohydramnios
•8. Antepartum haemorrhage
•9. Dystocia
•10. Postmaturity
•11. Prematurity

•1. Maternal complications e.g. pre-eclampsia, cardiovascular disease, cerebrovascular disease
•2. Multiple gestation
•3. Known fetal abnormality
•4. Patients with absolute or relative contra-indications for spinal anaesthesia e.g. infection in lumbar area, coagulation abnormalities, autonomic neuropathy, spinal deformities, other neurological diseases, hypovolemia due to any cause
•5. Maternal baseline SBP less than 100 mmHg
•6. Severely compromised fetus requiring immediate administration of general anaesthesia to mother
•7. Patients on monoamine oxidase inhibitors or tricyclic antidepressants
•8. History suggestive of mesenteric or peripheral vascular thrombosis

发起方

niversity College of Medical Sciences and Guru Teg Bahadur Hospital