NCT04530175已完成不适用
Modeling of Regional Citrate Anticoagulation With a Dialysate Containing Calcium in Intermittent Hemodialysis
University Hospital, Clermont-Ferrand1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2021年2月2日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Ionized calcium level
研究概览
简要总结
The primary purpose of this study is to validate a mathematical modeling of treatment by intermittent hemodialysis using regional citrate anticoagulation with a dialysate containing calcium
详细描述
The only visit to the study will be carried out during a usual dialysis session in the intensive care unit of Clermont-Ferrand University Hospital. In addition to the usual care, 2 blood samples will be taken from the blood circuit 1 hour after the start of the hemodialysis session by the nurse in charge of the patient.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Major patient;
- •Man or woman ;
- •Treated with intermittent hemodialysis for chronic renal failure;
- •In whom intermittent hemodialysis with citrate solution for regional anticoagulation is indicated;
- •Affiliated with a social security scheme;
- •Having given a signed agreement after detailed explanation of the protocol on the basis of the information sheet and likely to comply with it
排除标准
- •Severe hepato-cellular insufficiency (PT <50%, INR> 1.5 without anticoagulant);
- •Hemoglobin level <7 g / dL
- •Presenting a psychiatric pathology or cognitive impairment rendering him unable to give informed consent;
- •Persons under guardianship, curatorship, deprived of liberty or safeguard of justice
- •Pregnant or breastfeeding women
- •Patient's refusal to participate in the study.
结局指标
主要结局
Ionized calcium level
时间窗: day 0
measured at dialyzer inlet, in mmol/L
Total calcium level
时间窗: day 0
measured at dialyzer inlet, in mmol/L
Total citratemia
时间窗: day 0
measured at dialyzer inlet, in mmol/L
次要结局
未报告次要终点
研究者
研究点 (1)
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