NCT00542087已完成3 期
A Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of Etoricoxib 60 mg and Diclofenac Sodium 150 mg in Patient With Osteoarthritis of the Knee or Hip
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 516
- 主要终点
- This study will assess the effectiveness of the study drug vs. a comparator to treat successfully OA-related joint pain (judged by WOMAC pain subscale).
研究概览
简要总结
To compare the safety and tolerability of etoricoxib and diclofenac sodium in the treatment of osteoarthritis of the knee or hip during a six week period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient is at least 40 years old and diagnosed with osteoarthritis of the knee or hip
- •Has a history of treatment with NSAIDs with positive therapeutic benefit
- •Agree to limit alcohol intake to less than 7 drinks per week and avoid unusual strenuous activity
- •Females who are able to have children must have negative urine pregnancy tests
排除标准
- •Has rheumatoid arthritis, lupus, Paget's disease affecting the study joint, or Wilson's disease
- •History of acute ligament or meniscus damage to the study joint (knee or hip) within the past 2 years or arthroscopic surgery on the affected study joint with the past 6 months
- •Requires joint replacement
结局指标
主要结局
This study will assess the effectiveness of the study drug vs. a comparator to treat successfully OA-related joint pain (judged by WOMAC pain subscale).
次要结局
- The study drug will be safe and well tolerated during the course of the study.
研究者
相似试验
已完成
4 期
Safety and Efficacy of Celecoxib Versus Placebo in the Treatment of Knee Osteoarthritis in Patients Who Were Unresponsive to Naproxen and IbuprofenOsteoarthritis, KneeNCT00638807Pfizer's Upjohn has merged with Mylan to form Viatris Inc.388
已完成
4 期
A Study to Assess Etoricoxib Versus Diclofenac in Chinese Patients With Osteoarthritis of the Knee or Hip (0663-080)(COMPLETED)OsteoarthritisNCT00140972Organon and Co160
已完成
3 期
A Study of MK0663/Etoricoxib for Post-Abdominal Hysterectomy Surgery Pain (0663-097)(COMPLETED)Acute Pain Following a Total Abdominal HysterectomyNCT00788710Organon and Co430
已完成
4 期
Efficacy and Safety of Celecoxib Versus Ibuprofen in the Treatment of Osteoarthritis of the Knee (Europe)Osteoarthritis, KneeNCT00630929Pfizer's Upjohn has merged with Mylan to form Viatris Inc.388
已完成
4 期
Efficacy and Safety of Celecoxib Versus Ibuprofen in the Treatment of Osteoarthritis of the Knee (United States)Osteoarthritis, KneeNCT00620867Pfizer's Upjohn has merged with Mylan to form Viatris Inc.393