ISRCTN25542492已完成未知
HOME FIRST (Home Followed-up by the Infection Respiratory Support Team): a feasibility study
Royal Liverpool and Broadgreen University Hospitals NHS Trust (UK)0 个研究点目标入组 200 人开始时间: 2012年10月16日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 200
研究概览
简要总结
2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/24571705
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Patients with any of the following conditions:
- •1. Pneumonia - community-acquired (CAP) or hospital-acquired (HAP) - pneumonia definition - a series of clinical symptoms with radiological consolidation
- •N.B. All pneumonia CURB-65 scores will be considered but patients with CURB-65 =3 MUST have had at least 24hrs of in-patient observation before recruitment into the study.
- •2. Acute tracheo-bronchitis & acute bronchitis
- •3. Non-pneumonic lower respiratory tract infection
- •4. Influenza with respiratory manifestations
- •5. Infective exacerbation of bronchiectasis
- •6. Lung abscess
- •7. Pneumonia with concomitant COPD (if this service is not provided elsewhere)
- •Patient Suitability:
- •1. Simple pleural effusions only (if no diagnostic pleural tap performed please discuss)
- •2. Can manage ADLs with current support (immediate OT/physio/social assessment/care can be arranged prior to discharge (if needed) and continued at home)
- •3. Able to give fully informed consent
- •4. Has a phone
- •5. Age>18yrs old
- •6. EWS =2 AND SBP>90 (all observations must be stable for 12-24hrs) AND mild confusion only (defined as an 10-point AMTS =7)
- •7. All observations must be stable for 12-24hrs
- •8. Improving inflammatory markers (WCC/CRP)
- •9. Stable or improving U&Es
排除标准
- •1. Acute exacerbations of COPD - infective & non-infective (other services already provided)
- •2. Patients with CURB-65 >3 admitted<24hrs ago
- •3. Patients unable to manage at home even with maximal support from HOME FIRST (this may include some patients IV drug users, with ETOH excess or mental health problems)
- •4. Serious co-morbidities requiring hospital treatment (eg: CKD, CCF) or deemed unstable (significant AKD)
- •5. Suspected MI/raised TnI/T consistent with NSTEMI (Or acute ECG changes) within 5 days of discharge
- •6. Empyema or complicated parapneumonic effusion
- •7. SBP<90mmHg
- •8. Neutropenia
- •9. No fixed abode
- •10. Tuberculosis suspected
- •11. Well enough for discharge without HOME FIRST homecare support
- •12. Sats <92% on air - for patients without chronic respiratory illness
- •13. Sats <88% on air [except asthma sats must be >92%] - for patients with chronic respiratory illness. All such cases MUST be discussed as oxygen assessment may be needed.
研究者
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