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临床试验/ISRCTN25542492
ISRCTN25542492已完成未知

HOME FIRST (Home Followed-up by the Infection Respiratory Support Team): a feasibility study

Royal Liverpool and Broadgreen University Hospitals NHS Trust (UK)0 个研究点目标入组 200 人开始时间: 2012年10月16日最近更新:

试验速览

阶段
未知
状态
已完成
发起方
入组人数
200

研究概览

简要总结

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • Patients with any of the following conditions:
  • 1. Pneumonia - community-acquired (CAP) or hospital-acquired (HAP) - pneumonia definition - a series of clinical symptoms with radiological consolidation
  • N.B. All pneumonia CURB-65 scores will be considered but patients with CURB-65 =3 MUST have had at least 24hrs of in-patient observation before recruitment into the study.
  • 2. Acute tracheo-bronchitis & acute bronchitis
  • 3. Non-pneumonic lower respiratory tract infection
  • 4. Influenza with respiratory manifestations
  • 5. Infective exacerbation of bronchiectasis
  • 6. Lung abscess
  • 7. Pneumonia with concomitant COPD (if this service is not provided elsewhere)
  • Patient Suitability:
  • 1. Simple pleural effusions only (if no diagnostic pleural tap performed please discuss)
  • 2. Can manage ADLs with current support (immediate OT/physio/social assessment/care can be arranged prior to discharge (if needed) and continued at home)
  • 3. Able to give fully informed consent
  • 4. Has a phone
  • 5. Age>18yrs old
  • 6. EWS =2 AND SBP>90 (all observations must be stable for 12-24hrs) AND mild confusion only (defined as an 10-point AMTS =7)
  • 7. All observations must be stable for 12-24hrs
  • 8. Improving inflammatory markers (WCC/CRP)
  • 9. Stable or improving U&Es

排除标准

  • 1. Acute exacerbations of COPD - infective & non-infective (other services already provided)
  • 2. Patients with CURB-65 >3 admitted<24hrs ago
  • 3. Patients unable to manage at home even with maximal support from HOME FIRST (this may include some patients IV drug users, with ETOH excess or mental health problems)
  • 4. Serious co-morbidities requiring hospital treatment (eg: CKD, CCF) or deemed unstable (significant AKD)
  • 5. Suspected MI/raised TnI/T consistent with NSTEMI (Or acute ECG changes) within 5 days of discharge
  • 6. Empyema or complicated parapneumonic effusion
  • 7. SBP<90mmHg
  • 8. Neutropenia
  • 9. No fixed abode
  • 10. Tuberculosis suspected
  • 11. Well enough for discharge without HOME FIRST homecare support
  • 12. Sats <92% on air - for patients without chronic respiratory illness
  • 13. Sats <88% on air [except asthma sats must be >92%] - for patients with chronic respiratory illness. All such cases MUST be discussed as oxygen assessment may be needed.

研究者

发起方
Royal Liverpool and Broadgreen University Hospitals NHS Trust (UK)

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