Risk Factors for Inter-eye Asymmetry in Keratoconus Severity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 154
- 试验地点
- 1
- 主要终点
- Risk factors for inter-eye keratoconus asymmetry in terms of severity
研究概览
简要总结
Observational study comparing patients with inter-eye asymmetric keratoconus with patients with inter-eye symmetric keratoconus.
详细描述
Detailed description: Keratoconus is a condition resulting in corneal thinning and visual impairment due to irregular astigmatism. Most cases are bilateral, although the severity is often asymmetric between both eyes. The aim of our study is to examine risk factors for inter-eye asymmetry in terms of severity in patients with a confirmed diagnosis of keratoconus. Patients were reviewed for keratoconus staging for each eye according to the Amsler-Krumeich classification to define asymmetry and separated in groups according to the laterality of the worst eye and in a group where both eyes were symmetric in terms of asymmetry. A multivariate logistic regression was performed on various risk factors to explore keratoconus inter-eye asymmetry.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients presenting to the attending ophthalmologist during the study period with previously diagnosed unilateral or bilateral keratoconus
- •Patients newly diagnosed with unilateral or bilateral keratoconus during the study period.
排除标准
- •Previous corneal surgery
- •Previous corneal crosslinking
- •Previous keratoplasty
- •Previous placement of intrastromal corneal rings
研究组 & 干预措施
cohort of Patients with keratoconus
Patients presenting to the attending ophthalmologist during the study period with previously diagnosed unilateral or bilateral keratoconus or (ii) patients newly diagnosed with unilateral or bilateral keratoconus during the study period.
干预措施: Questionnaire (Behavioral)
结局指标
主要结局
Risk factors for inter-eye keratoconus asymmetry in terms of severity
时间窗: Day 1
Logistic regression
次要结局
未报告次要终点
