Exertional Desaturation as a Marker of Risk - Validation Study for the 40-steps-test; A Multi-centre Prospective Observational Cohort Study
试验速览
- 阶段
- 不适用
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Death
研究概览
简要总结
Exertional desaturation is a feature of COVID-19. The study will measure vital signs of patients discharge by practitioners in primary care, secondary care or by paramedic practitioners. Patients will then undertake a 40-steps on the spot walk followed by measurements of heart rate and oxygen saturations for up to two minutes. Association of desaturation with 30 days hospital admission and mortality will be reported.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients are being considered for discharge to independent care
- •Participant is willing and able to give informed consent for participation in the study.
- •Patient with independent, stable, gait
- •Patient is alert, attentive, coherent, and calm
- •Male or Female, aged 18 years or above.
排除标准
- •Minor injuries
- •Elective surgery patients
- •Post-operative patients at discharge
- •Requires supplemental oxygen
- •Shortness of breath at rest (i.e. Borg or Numerical Rating Scale >=2)
- •Unstable angina
- •Patients on long-term-oxygen therapy
- •Pregnancy as stated by patient
- •Oxygen saturations < 95% on room air
- •Resting heart rate > 100 bpm
- •Resting respiratory rate > 25 bpm
- •ECG with signs of acute ischemia in patients where an ECG has been requested by the treating clinician
- •National Early Warning Score of 5 or more
- •Nursing home residents, or those being transferred to a nursing home or similar care facility
结局指标
主要结局
Death
时间窗: 30 days
Death within 30 days of the test
Change in decision to discharge
时间窗: 24 hours
1. No change 2. Further investigations 3. Hospital admission a) No change b) Further investigations c) Hospital admission
Hospital
时间窗: 30 days
Admission to hospital within 30 days of the test
次要结局
- Change in respiratory rate(Within 2 minutes of completion of the test)
- Change in oxygen saturations(Within 2 minutes of completion of the test)
- Change in breathlessness(Within 2 minutes of completion of the test)
- Feasibility of the 40-steps test(12 months)
- Change in heart rate(Within 2 minutes of completion of the test)
研究者
Dr Christian P Subbe
Consultant Physician
Betsi Cadwaladr University Health Board