临床试验/NCT00186576

NCT00186576已完成不适用

Non-Myeloablative Allogeneic Hematopoietic Cell Transplantation for Treatment of Myelodysplastic Syndromes and Myeloproliferative Disorders (Except CML)

Stanford University2 个研究点分布在 1 个国家目标入组 40 人开始时间: 2001年12月最近更新: 2010年10月14日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Stanford University
入组人数: 40
试验地点: 2
主要终点: Efficacy of transplant

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

To improve survival outcomes for patients with MDS and MPD with a nonmyeloablative allogeneic hematopoietic cell transplant.

详细描述

Non-Myeloablative Allogeneic Hematopoietic Cell Transplantation for Treatment of Myelodysplastic Syndromes and Myeloproliferative Disorders (Except CML)

研究设计

研究类型: Interventional
分配方式: Non Randomized
干预模型: Single Group
主要目的: Treatment
盲法: None

入排标准

年龄范围: 18 Years 至 75 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Myelodysplastic Syndromes
•Myeloproliferative Disorders
•HLA matched donor available

排除标准

•organ dysfunction
•HIV positive

结局指标

主要结局

Efficacy of transplant

时间窗: 1 year

次要结局

safety profile of nonmyeloablative transplant, graft versus host disease, graft rejection, non-relapse mortality, use of donor lymphocyte infusion(1 year)

研究者

发起方

Stanford University

申办方类型

Other

研究点 (2)

Loading locations...

相似试验

已完成

2 期

Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic DisordersALLNon-Hodgkin's LymphomaHodgkin's LymphomaMyeloproliferative DisorderMultiple MyelomaCLLMyelodysplastic SyndromeAMLAplastic Anemia

NCT00533923Beth Israel Deaconess Medical Center25

已完成

1 期

Enhancing Graft vs Leukemia Via Delayed Ex-Vivo Co-Stimulated DLI After Non-Myeloablative Stem Cell TransplantationAcute Myelogenous LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome

NCT00374933Abramson Cancer Center at Penn Medicine18

已完成

早期 1 期

Pilot Study of Non-Myeloablative, HLA-Matched Allogeneic Stem Cell Transplantation for Pediatric Hematopoietic MalignanciesLymphocytic LeukemiaMixed Cell LeukemiaNon Hodgkin's LymphomaCMLALLLymphomaMyelodysplastic SyndromeAMLHodgkin Lymphoma

NCT00013533National Cancer Institute (NCI)30

已完成

不适用

A Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative RegimenHemoglobinopathiesSickle Cell DiseaseThalassemia

NCT00427661University of Pittsburgh8

Unknown

1 期

Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Pancreatic CancerPancreatic Cancer Stage IIIPancreatic Cancer Stage IV

NCT03236883Tianjin Medical University Cancer Institute and Hospital30