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临床试验/NCT06515574
NCT06515574
招募中
不适用

Effect of Developmental Care on Very Low Birth Weight Infants: a Stepped-wedge Cluster Randomised Trial

Children's Hospital of Fudan University2 个研究点 分布在 1 个国家目标入组 1,600 人2024年8月30日
适应症Intervention
干预措施developmental care

概览

阶段
不适用
干预措施
developmental care
疾病 / 适应症
Intervention
发起方
Children's Hospital of Fudan University
入组人数
1600
试验地点
2
主要终点
Length of hospital stay
状态
招募中
最后更新
上个月

概览

简要总结

The goal of this clinical trial is to learn if developmental care works when implemented in very low birth weight infants. The main questions it aims to answer are:

  • Does developmental care shorten the length of hospital stay in the very low birth weight infants?
  • Does developmental care increase the opportunity of family centered care in the very low birth weight infants? The clinical trial will use a 36-month stepped-wedge cluster-randomised trial conducted across 40 Neonatal intensive care units . A developmental care bundle will be tailored to meet the identified needs of participating NICUs.

详细描述

Developmental care in the NICU focuses on creating a nurturing environment that supports the physical, emotional, and developmental needs of premature infants. This approach includes strategies like minimizing unnecessary noise and light, ensuring appropriate positioning and handling of infants, promoting skin-to-skin contact, and facilitating parental involvement in care. The clinical trial investigates the effectiveness of developmental care in very low birth weight (VLBW) infants. The primary objectives are to determine whether developmental care can (1) reduce the length of hospital stay and (2) enhance the opportunity for family-centered care in these infants. The study employs a 36-month stepped-wedge cluster-randomised trial design, involving 40 Neonatal Intensive Care Units (NICUs). In this trial, all NICUs will eventually receive the intervention, but the order in which they start implementing the developmental care bundle will be randomized. This approach allows each NICU to serve as its own control, comparing outcomes before and after the intervention. Data collection will occur at multiple time points before and after the implementation of the developmental care bundle, enabling a comprehensive analysis of its impact. By tailoring interventions to each NICU's specific context and needs, the study aims to generate robust evidence on the benefits of developmental care for VLBW infants and their families.

注册库
clinicaltrials.gov
开始日期
2024年8月30日
结束日期
2027年12月1日
最后更新
上个月
研究类型
Interventional
研究设计
Sequential
性别
All

研究者

入排标准

入选标准

  • Birth weights less than 1500 g
  • Admitted or transported to a level III NICU within 24h of birth

排除标准

  • Severe congenital malformations
  • various chromosomal disorders
  • genetic metabolic diseases,
  • severe neurological disorders

研究组 & 干预措施

Developmental care

In stage 1, participant in this arm will receive the developmental care

干预措施: developmental care

Usual care

Participant in this arm will receive the usual care

结局指标

主要结局

Length of hospital stay

时间窗: From the day admitted into the NICU until day on discharge, generally assessed up to 1 year

Length of hospital stay (in days)

次要结局

  • Skin to skin care duration(From the day admitted into the NICU until day on discharge, generally assessed up to 1 year)

研究点 (2)

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