Effectiveness of a Short-term Mixed Exercise Program for Treating Sarcopenia in Hospitalized Patients Aged 80 Years and Older
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 121
- 主要终点
- The change of activities of daily living from the baseline to the end of the 2-week intervention
研究概览
简要总结
Most previous clinical trials that addressed exercise for sarcopenic elderly subjects focused on community-dwelling older adults who were relatively healthy. There is a notable paucity of high-quality research investigating the effects and feasibility of exercise for hospitalized or institutionalized older people, who are generally frailer and more severe in functional impairment than those living in the community. Moreover, most reported exercise programs were of long-term duration, which typically lasted 3 to 6 months with two sessions per week. It remains unclear whether short-term exercise would be effective for treating sarcopenia. Therefore, the investigators aimed to assess the effectiveness of short-term exercise for treating sarcopenia in hospitalized older patients aged 80 years and over.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 80 Years 至 102 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged ≥80 years;
- •being able to ambulate (assistance was acceptable);
- •being able to communicate and collaborate with the physiotherapist;
- •with sarcopenia defined by the AWGS criteria ;
排除标准
- •terminal illness;
- •uncontrolled heart failure;
- •myocardial infarction within the past three months;
- •uncontrolled respiratory failure;
- •bone fractures within the past three months;
- •acute pulmonary embolism;
- •major surgery within the past three months;
- •uncontrolled arrhythmia;
- •refusal to participate in this study.
研究组 & 干预措施
Intervention group
a mixed exercise program including aerobic, balance, and resistance exercises that were personally tailored.
干预措施: balance training (Behavioral)
Intervention group
a mixed exercise program including aerobic, balance, and resistance exercises that were personally tailored.
干预措施: resistance training (Behavioral)
Intervention group
a mixed exercise program including aerobic, balance, and resistance exercises that were personally tailored.
干预措施: aerobic exercise (Behavioral)
control group
usual care
干预措施: usual care (Behavioral)
结局指标
主要结局
The change of activities of daily living from the baseline to the end of the 2-week intervention
时间窗: 2 weeks
Basic activities of daily living (BADL) assessed by Barthel Index. The total score for Barthel Index ranges from 0 (worst) to 100 (best) points.
次要结局
- The change of handgrip strength(2 weeks)
- The change of gait speed(2 weeks)
- The change of the score of Short Physical Performance Battery(2 weeks)
- The change of the score of Timed Up and Go test(2 weeks)
研究者
Yuxiang Liang
Physiotherapist
West China Hospital