NCT00729287已完成3 期
Phase III Randomized Chemoprevention Study of Selenium on the Recurrence of Non-invasive Bladder Cancer
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- KU Leuven
- 入组人数
- 276
- 试验地点
- 2
- 主要终点
- Effect of selenium in preventing the recurrence of bladder cancer
研究概览
简要总结
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of selenium may keep bladder cancer from growing or coming back. It is not yet known whether selenium is more effective than a placebo in preventing cancer recurrence in patients with bladder cancer.
PURPOSE: This randomized phase III trial is studying selenium to see how well it works compared with a placebo in preventing cancer recurrence in patients with bladder cancer.
详细描述
OBJECTIVES:
Primary
- To determine the effect of selenium, when administered with standard care, in preventing the recurrence of bladder cancer in patients with non-muscle-invasive transitional cell carcinoma of the bladder at risk for recurrence.
Secondary
- To determine the effect of selenium on the recurrence of bladder cancer, in terms of histological type, number, and size.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Effect of selenium in preventing the recurrence of bladder cancer
时间窗: 3 years
次要结局
- Effect of selenium on the progression of bladder cancer, in terms of histological type, number, and size(3 years)
研究者
研究点 (2)
Loading locations...
相似试验
已完成
3 期
Vaccine To Prevent Cervical Intraepithelial Neoplasia or Cervical Cancer in Younger Healthy ParticipantsPrecancerous ConditionCervical CancerNCT00128661GlaxoSmithKline7,466
已完成
3 期
Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung CancerLung CancerNCT00008385ECOG-ACRIN Cancer Research Group1,772
已完成
3 期
A Phase III, Randomized, Study of Aspirin and Esomeprazole Chemoprevention in Barrett's MetaplasiaPrecancerous ConditionEsophageal CancerNCT00357682University of Oxford2,557
已完成
3 期
S0000 Selenium and Vitamin E in Preventing Prostate CancerProstate CancerNCT00006392SWOG Cancer Research Network35,533
撤回
2 期
Celecoxib in Preventing Skin Cancer in Patients With Actinic KeratosesPrecancerous ConditionNCT00027976University of Alabama at Birmingham