跳至主要内容
临床试验/CTRI/2024/07/070412
CTRI/2024/07/070412招募中不适用

Clinical utility of red cell distribution width as a prognostic marker in sepsis.

Kasturba Medical College1 个研究点 分布在 1 个国家目标入组 160 人开始时间: 2024年7月22日最近更新:

试验速览

阶段
不适用
状态
招募中
入组人数
160
试验地点
1
主要终点
Exploring the clinical utility of red cell distribution width (RDW) in predicting outcome in sepsis patients.

研究概览

简要总结

The study will be done after obtaining approval from IEC and CTRI clearance. The written consent will be taken from all the patients in the language that they understand. If the patient is not able to give consent then consent shall be taken from the next kin. Our study is a prospective, longitudinal study that includes patients who are diagnosed with sepsis. Patients will be recruited from wards and ICUs admitted under the Department of General Medicine during the study period. RDW shall be noted at the time of presentation to the hospital. SOFA score of the patients will be calculated initially to diagnose sepsis. Serial RDW levels might be collected from the labs if available. The patient will be observed throughout his stay in the hospital until he recovers or expires. The outcome will be noted. Patients will be followed up for 1 month. Patients who leave against medical advice will not be included in the study. Other important data like the hospital number of the patient, history of present illness, comorbidities, habits like alcohol and smoking, laboratory parameters like LFT, RFT, electrolytes, blood culture sensitivity, urine, and pus culture sensitivity will be noted if available. Examination findings including vitals and systemic examination findings shall be noted. XRAY, ECG, duration of hospital stay, ionotropic requirement, dialysis requirement, and duration of ICU stay shall also be noted. Patient safety and confidentiality will not be compromised throughout the study.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 90.00 Year(s)(—)
性别
All

入选标准

  • The patients whose sepsis criteria were met during admission were included in the study.
  • Patients (18 years and older) diagnosed with sepsis according to established criteria – SEPSIS 3 guidelines-SOFA score Sepsis is considered if the patient had a confirmed or suspected infection with organ dysfunction represented by an increase of SOFA score of 2 or more points.

排除标准

  • Patients with pre-existing hematological disorders affecting RDW Iron Deficiency Anemia(hb<12 in females,hb<13 in males) B12 & Folate deficiency Sickle cell anemia.
  • CKD-ESRD/Stage>3 Recent blood transfusions in last 1 month Recent surgeries,trauma Chronic alcoholics.

结局指标

主要结局

Exploring the clinical utility of red cell distribution width (RDW) in predicting outcome in sepsis patients.

时间窗: 2 YEARS

次要结局

  • -To determine the risk factors in patients admitted with sepsis.

研究者

申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

KILLAMSETTY ADITYA SAI

Kasturba Medical College,Manipal

研究点 (1)

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