ISRCTN70923932已完成未知
A multi-centre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and healthcare resource use following cardiac surgery
niversity Hospitals Bristol NHS Foundation Trust (UK)0 个研究点目标入组 2,000 人开始时间: 2008年9月9日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 2,000
研究概览
简要总结
2014 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/24675014 2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25760354 2015 statistical analysis plan in: http://www.ncbi.nlm.nih.gov/pubmed/25881049 2016 results in: https://www.ncbi.nlm.nih.gov/pubmed/27481621
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Current inclusion criteria as of 24/08/2010:
- •1. Adults of either sex, aged =16
- •2. Post-operative nadir Hb / Hct level below 9.0 g / dL / 27
- •Previous inclusion criteria from 01/09/2009 to 24/08/2010:
- •1. Adults of either sex, aged =16 and <80 years
- •2. Post-operative nadir Hb / Hct level below 9.0 g / dL / 27
- •Initial information at time of registration:
- •1. Adults of either sex, aged =16 and <80 years
- •2. Post-operative nadir Hb level below 9.0 g/d
排除标准
- •Current information as of 01/09/2009:
- •1. Patients who are prevented from having blood and blood products according to a system of beliefs (e.g., Jehovah's Witnesses)
- •2. Patients with congenital or acquired platelet, red cell or clotting disorders
- •3. Patients with ongoing or recurrent sepsis
- •4. Patients who were unable to give full informed consent for the study (e.g., learning or language difficulties)
- •5. Patients with critical limb ischaemia
- •6. Patients undergoing emergency surgery
- •7. Patients already participating in another interventional research study
- •Initial information at time of registration:
- •1. Patients who are prevented from having blood and blood products according to a system of beliefs (e.g., Jehovah's Witnesses)
- •2. Patients with congenital or acquired platelet, red cell or clotting disorders
- •3. Patients with ongoing or recurrent systemic sepsis
- •4. Patients who were unable to give full informed consent for the study (e.g., learning or language difficulties)
- •5. Patients with a critical carotid artery stenosis (>75%) or critical limb ischaemia
- •6. Patients with flow limiting (>70% luminal stenosis) coronary artery disease not undergoing complete revascularisation
研究者
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