Metabolic Effects of a Thermogenic Ready-to-drink Beverage
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Resting metabolic rate
研究概览
简要总结
This study is a randomized, double-blind, placebo-controlled crossover trial examining the metabolic effects of a novel ready-to-drink (RTD) beverage. Healthy adult males and females will be recruited for participation. Each participant will complete two conditions in random order: 1) RTD thermogenic beverage ; and 2) placebo (consisting of the flavoring of the thermogenic beverage without the active ingredients). In each condition, metabolism (resting metabolic rate), hemodynamic (heart rate and blood pressure), and subjective (ratings of energy, focus, concentration, alertness, and mood) assessments will be completed at baseline, 30 minutes after beverage consumption, and 30 minutes after the second round of assessments.
详细描述
The primary purpose of this study is to report the metabolic effects of a new ready-to-drink (RTD) version of EHP Labs OxyShred Thermogenic Fat Burner. Additionally, the effect of this product on hemodynamic variables and subjective ratings of energy, focus, concentration, alertness, and mood will be reported.
OxyShred Thermogenic Fat Burner (EHP Labs) is a popular dietary supplement for those seeking to increase energy and reduce body fat. While this product is commercially available as a powdered dietary supplement, a new RTD formulation is currently being developed. While the RTD formula will be similar to the current version of the product, research specifically conducted with the RTD version is needed to definitively support product claims and demonstrate the potential effects of this novel product. Additionally, there is a need to better understand the effects of caffeine-containing, thermogenic products among the variety of groups who may consume these products (e.g., males vs. females, inactive vs. active, etc.).
This study is a randomized, double-blind, placebo-controlled crossover trial examining the metabolic effects of a novel ready-to-drink (RTD) beverage. Healthy adult males and females will be recruited for participation. Each participant will complete two conditions in random order: 1) RTD thermogenic beverage ; and 2) placebo (consisting of the flavoring of the thermogenic beverage without the active ingredients). In each condition, metabolism (resting metabolic rate), hemodynamic (heart rate and blood pressure), and subjective (ratings of energy, focus, concentration, alertness, and mood) assessments will be completed at baseline, 30 minutes after beverage consumption, and 30 minutes after the second round of assessments.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The inclusion criteria are:
- •Between the ages of 18 and
- •Body mass between 50 - 110 kg (110 - 220 lbs.).
- •Either: (A) Resistance-trained, defined as completing 3+ resistance training sessions per week for at least two years prior to screening; full body (all upper body and lower body major muscle groups) must be trained at least once weekly, OR (B) non-resistance trained, defined as never having followed a structured resistance training program.
- •Perform ≤ 30 minutes of high-intensity interval training per week.
- •Perform ≤ 60 minutes of steady state endurance exercise per week.
- •Regular caffeine consumption (due to the presence of caffeine in the commercially available dietary supplement). This will be defined as an average self-reported daily intake of 200+ mg of caffeine, which is equivalent to approximately 2 cups of coffee.
排除标准
- •Failing to meet any of the aforementioned inclusion criteria.
- •Presence of any known disease or medical condition which could be negatively affected by consumption of the beverage. This includes cardiovascular disease or condition; liver disease or disorder; other metabolic disease or disorder; or other conditions that could reasonably be deemed to contraindicate the study protocol.
- •Pregnant or breastfeeding, based on self-report (for female participants).
- •Taking medication which could reasonably make participation unsafe for the participant or influence study outcomes. Specifically, use of any prescription stimulant (e.g., dextroamphetamine (Dexedrine®), dextroamphetamine/amphetamine combination product (Adderall®), methylphenidate (Ritalin®, Concerta®), or similar stimulants) precludes participation in this study.
- •Self-reported caffeine sensitivity, as indicated by unwanted side effects when caffeine is consumed.
- •Allergy to any of the ingredients in the RTD beverage.
- •Presence of a pacemaker or other implanted electrical device
- •Self-reported claustrophobia (due to metabolism testing)
研究组 & 干预措施
Thermogenic Ready-to-drink Beverage
Arm in which a thermogenic ready-to-drink beverage is ingested.
干预措施: Thermogenic Ready-to-drink Beverage (Other)
Placebo Ready-to-drink Beverage
Arm in which a placebo ready-to-drink beverage is ingested.
干预措施: Placebo Ready-to-drink Beverage (Other)
结局指标
主要结局
Resting metabolic rate
时间窗: 140 minutes
Resting metabolic rate from indirect calorimetry expressed as kilocalories expended per unit time (e.g., kcal/min).
Respiratory quotient
时间窗: 140 minutes
Respiratory quotient from indirect calorimetry in arbitrary units, which reflects the proportion of carbohydrate and fat oxidized at rest.
次要结局
- Subjective rating of energy(140 minutes)
- Subjective rating of focus(140 minutes)
- Heart rate(140 minutes)
- Subjective rating of concentration(140 minutes)
- Subjective rating of alertness(140 minutes)
- Subjective rating of mood(140 minutes)
- Systolic blood pressure(140 minutes)
- Diastolic blood pressure(140 minutes)