CTRI/2017/11/010485尚未招募未知
A prospective open randomized clinical trial of non-invasive ventilation versus standard therapy for children hospitalized with an acute exacerbation of asthma.
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Children >24 months old, presenting to the Pediatric Emergency with acute asthma. Acute asthma will be diagnosed on the basis of (i) respiratory rate greater than WHOâ??s age-dependent WHO criteria; (ii) history of similar previous episodes or physician diagnosed asthma; and (iii) wheezing heard on auscultation.
排除标准
- •1. Clinical suspicion of bacterial pneumonia on the basis of: focal crackles or bronchial breathing, and/or chest x-ray findings suggesting pneumonia (consolidation, major infiltrates, pleural effusion).
- •2. Impending respiratory failure at presentation requiring direct PICU admission
- •3. Any contraindication to BiPAP use including altered mental status, recent bowel surgery, intractable vomiting, inability to protect airway
- •4. Current tracheostomy, home ventilation (IPPV or NIPPV) or home oxygen requirement
- •5. Prior receipt of oral steroid at the time of presentation
- •6. History of congenital heart disease or chronic respiratory disease (including bronchopulmonary dysplasia, cystic fibrosis, pulmonary hypertension)
- •7. Craniofacial abnormality
- •8. Pneumothorax.
研究者
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