NCT02083263已完成不适用
Study of Non Invasive Ventilation With High Pressure as Airways Clearance Technique in Adults Patients With Cystic Fibrosis
Karolinska University Hospital2 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2012年10月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 32
- 试验地点
- 2
- 主要终点
- Lung Function: Lung Clearance Index
研究概览
简要总结
With the use of Non invasive ventilation the patients with cystic fibrosis will have better lung function (FEV1).
详细描述
3 months intervention between PEP an Bilevel. The patients will follow up under 3 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with CF older than 18 years
- •FEV1 between 20% and 69% of predictive.
- •No acute exacerbation.
- •No Burkhordelia Cepacia/MRSA colonization.
排除标准
- •Children under 18 year
- •acute exacerbation.
结局指标
主要结局
Lung Function: Lung Clearance Index
时间窗: up to 3 months
Lung clearance index was calculated as the number of lung volume turnovers (cumulative expired volume divided by the functional residual capacity) required to reduce end-tidal nitrogen concentration to 1/40th of the starting value.
次要结局
- Blood Gases:1 Month After Chest Physiotherapy Will Take Blood Gases (Kpa).(1 month)
研究者
Cecilia Rodriguez
Specialist Physiotherapist
Karolinska University Hospital
研究点 (2)
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