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临床试验/NCT01918137
NCT01918137Unknown不适用

A Randomised Trial of Effect of Deep-fried Chocolate Bar and Porridge Upon Cerebrovascular Reactivity in Healthy Adult Volunteers

NHS Greater Glasgow and Clyde2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2013年8月最近更新:
适应症

试验速览

阶段
不适用
入组人数
24
试验地点
2
主要终点
Change in breath hold index after ingestion of deep-fried chocolate bar compared with change after porridge ingestion

研究概览

简要总结

The deep fried chocolate bar is a snack that the international community strongly associates with Scotland. It has previously been cited as being "a symbol of all that is wrong with the high-fat, high-sugar Scottish diet". Despite the snack's reputation, no medical research has been performed to examine the effects of consuming a deep fried chocolate bar on the human body.

In contrast to the deep fried chocolate bar, porridge has been shown to reduce the risk of cardiovascular disease, but its effect on cerebral blood flow has yet to be directly assessed.

This study will focus on the potential (patho)physiological cerebrovascular effects of the deep fried chocolate bar and porridge. The research question to be addressed in this study is "Does eating a deep fried chocolate bar or bowl of porridge induce changes in cerebral blood flow and cereborvascular reactivity in healthy adults?"

To assess the acute effects on eating either food on blood flow through the largest artery in the brain, the investigators will give healthy volunteers one regular-sized deep-fried chocolate bar or a bowl of porridge. Blood flow through the largest artery in the brain will be assessed using simple ultrasounds tests. The investigators aim to recruit 24 volunterrs who will visit twice, consuming a different food on each visit.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • BMI between 18 and 30
  • No regular medication
  • Able to provide informed consent

排除标准

  • Distaste for or contraindication to deep-fried chocolate bar or porridge ingestion
  • inability to perform breath-hold

结局指标

主要结局

Change in breath hold index after ingestion of deep-fried chocolate bar compared with change after porridge ingestion

时间窗: 4 weeks

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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