Sweet Consumption and Subsequent Sweet Food Preferences and Intakes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 104
- 试验地点
- 2
- 主要终点
- Sweet Food Preferences
研究概览
简要总结
This study will assess the effects of repeated sweet versus non-sweet food consumption on subsequent sweet and non-sweet food preferences and intakes.
详细描述
Participants will be randomized to receive instructions to either increase, decrease or make no change to sweet food consumption for 6 days, and impacts on food preferences and intakes will be assessed at baseline and after 1 week. Preferences for sweet and non-sweet foods will be assessed during a taste test at each assessment time, where six different foods will be rated. Sweet and non-sweet food consumption will also be measured at a subsequent breakfast at the assessment time. Buffet meals composed of sweet and non-sweet foods suitable for consumption at breakfast will be provided ad-libitum.
A subset of participants (selected at random) (10 participants randomized to increase sweet food consumption and 10 participants randomized to decrease sweet food consumption) will also be assessed via MRI and fMRI scanning to investigate brain structure and functional connectivity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Investigator, Outcomes Assessor)
盲法说明
Investigators, outcome assessors and analysts will be masked. It is not possible to mask participants.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •aged 18-65 years;
- •habitually consume breakfast;
- •able to provide consent and complete all study materials;
- •able to attend Bournemouth University for testing.
- •Exclusion criteria:
- •individuals who are pregnant or breastfeeding;
- •underweight (BMI <18.5);
- •have pre-existing clinical conditions such as diabetes mellitus, eating disorders, Crohn's disease and other illness's leading to participants receiving external nutritional advice and dietary restrictions;
- •have pre-existing medical conditions affecting swallow ability, taste and smell perception;
- •currently or within 3 months of starting the study are following a specific dietary programme (e.g.: Slimming World);
- •current smokers or have smoked within 3 months of the study start date.
排除标准
- 未提供
结局指标
主要结局
Sweet Food Preferences
时间窗: Week 1
Preferences for various sweet foods/fluids, assessed using a taste test, where participants sample several sweet and non-sweet foods and rate them for pleasantness on a 100mm Visual Analogue Scale, from 0 to 100mm. Higher scores signify stronger preferences
Sweet Food Choices
时间窗: Week 1
Selection of sweet foods/fluids at a given meal, assessed where participants can consume freely from a meal composed of sweet and non-sweet foods, and proportion of sweet foods consumed is measured as a percentage of weight consumed
次要结局
- Hunger and Thirst(Week 1)
- Sweet Food Perceptions(Week 1)
- MRI Static Brain Scan (Subset of Participants Only)(Baseline to week 1)
- fMRI Composite Functional Brain Scan (Subset of Participants Only)(Baseline to week 1)